9B98
Crystal structure of the human PAD2 protein bound to small molecule
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000791 | cellular_component | euchromatin |
| A | 0004668 | molecular_function | protein-arginine deiminase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006338 | biological_process | chromatin remodeling |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0021762 | biological_process | substantia nigra development |
| A | 0030331 | molecular_function | nuclear estrogen receptor binding |
| A | 0030520 | biological_process | estrogen receptor signaling pathway |
| A | 0035578 | cellular_component | azurophil granule lumen |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0045815 | biological_process | transcription initiation-coupled chromatin remodeling |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070100 | biological_process | negative regulation of chemokine-mediated signaling pathway |
| A | 0140794 | molecular_function | histone arginine deiminase activity |
| A | 0140798 | molecular_function | histone H3R26 arginine deiminase activity |
| A | 1901624 | biological_process | negative regulation of lymphocyte chemotaxis |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25621824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N20","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N22","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N24","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N25","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N26","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25621824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N20","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N22","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N24","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N26","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25621824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N20","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N22","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N24","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N25","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N26","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25621824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N25","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N26","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25621824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N25","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N26","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25621824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N26","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25621824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N25","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N26","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2L","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"4N25","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N26","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25621824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2I","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25621824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N2I","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
