9B1J
Urate bound human URAT1 in the inward-facing state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0009410 | biological_process | response to xenobiotic stimulus |
| A | 0015143 | molecular_function | urate transmembrane transporter activity |
| A | 0015711 | biological_process | organic anion transport |
| A | 0015747 | biological_process | urate transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016324 | cellular_component | apical plasma membrane |
| A | 0019725 | biological_process | cellular homeostasis |
| A | 0030165 | molecular_function | PDZ domain binding |
| A | 0031526 | cellular_component | brush border membrane |
| A | 0032869 | biological_process | cellular response to insulin stimulus |
| A | 0046415 | biological_process | urate metabolic process |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0097744 | biological_process | renal urate salt excretion |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 240 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU9-MET29 | |
| A | VAL435-LEU455 | |
| A | GLY466-GLY486 | |
| A | LEU495-GLN515 | |
| A | GLN146-ARG166 | |
| A | THR174-PRO194 | |
| A | VAL195-GLY215 | |
| A | THR232-VAL252 | |
| A | LEU260-ALA280 | |
| A | LEU351-GLY371 | |
| A | GLN378-HIS398 | |
| A | ALA407-GLY427 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q8CFZ5 |
| Chain | Residue | Details |
| A | SER542 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN56 | |
| A | ALA102 |
