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9B1D

Cryo-EM structure of native SWR1 bound to DNA (composite structure)

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0000725biological_processrecombinational repair
A0000785cellular_componentchromatin
A0000812cellular_componentSwr1 complex
A0003677molecular_functionDNA binding
A0004386molecular_functionhelicase activity
A0005198molecular_functionstructural molecule activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005829cellular_componentcytosol
A0006325biological_processchromatin organization
A0006338biological_processchromatin remodeling
A0006355biological_processregulation of DNA-templated transcription
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0031492molecular_functionnucleosomal DNA binding
A0042393molecular_functionhistone binding
A0060090molecular_functionmolecular adaptor activity
B0000785cellular_componentchromatin
B0000812cellular_componentSwr1 complex
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0006325biological_processchromatin organization
B0006338biological_processchromatin remodeling
B0006355biological_processregulation of DNA-templated transcription
B0042393molecular_functionhistone binding
C0000785cellular_componentchromatin
C0000812cellular_componentSwr1 complex
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0006325biological_processchromatin organization
C0006338biological_processchromatin remodeling
C0006355biological_processregulation of DNA-templated transcription
C0031491molecular_functionnucleosome binding
C0034399cellular_componentnuclear periphery
D0000785cellular_componentchromatin
D0000812cellular_componentSwr1 complex
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0006325biological_processchromatin organization
D0006338biological_processchromatin remodeling
D0006355biological_processregulation of DNA-templated transcription
D0006623biological_processprotein targeting to vacuole
D0008270molecular_functionzinc ion binding
D0031491molecular_functionnucleosome binding
D0046872molecular_functionmetal ion binding
E0000166molecular_functionnucleotide binding
E0000492biological_processbox C/D snoRNP assembly
E0000785cellular_componentchromatin
E0000812cellular_componentSwr1 complex
E0003678molecular_functionDNA helicase activity
E0004386molecular_functionhelicase activity
E0005515molecular_functionprotein binding
E0005524molecular_functionATP binding
E0005634cellular_componentnucleus
E0006281biological_processDNA repair
E0006325biological_processchromatin organization
E0006338biological_processchromatin remodeling
E0006355biological_processregulation of DNA-templated transcription
E0006357biological_processregulation of transcription by RNA polymerase II
E0006974biological_processDNA damage response
E0008094molecular_functionATP-dependent activity, acting on DNA
E0008643biological_processcarbohydrate transport
E0015144molecular_functioncarbohydrate transmembrane transporter activity
E0016787molecular_functionhydrolase activity
E0016887molecular_functionATP hydrolysis activity
E0031011cellular_componentIno80 complex
E0035267cellular_componentNuA4 histone acetyltransferase complex
E0043138molecular_function3'-5' DNA helicase activity
E0043139molecular_function5'-3' DNA helicase activity
E0050821biological_processprotein stabilization
E0055085biological_processtransmembrane transport
E0097255cellular_componentR2TP complex
E0110078cellular_componentTTT Hsp90 cochaperone complex
F0000166molecular_functionnucleotide binding
F0000492biological_processbox C/D snoRNP assembly
F0000785cellular_componentchromatin
F0000812cellular_componentSwr1 complex
F0003678molecular_functionDNA helicase activity
F0004386molecular_functionhelicase activity
F0005515molecular_functionprotein binding
F0005524molecular_functionATP binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0006281biological_processDNA repair
F0006325biological_processchromatin organization
F0006338biological_processchromatin remodeling
F0006355biological_processregulation of DNA-templated transcription
F0006357biological_processregulation of transcription by RNA polymerase II
F0006364biological_processrRNA processing
F0006974biological_processDNA damage response
F0008094molecular_functionATP-dependent activity, acting on DNA
F0016787molecular_functionhydrolase activity
F0016887molecular_functionATP hydrolysis activity
F0031011cellular_componentIno80 complex
F0035267cellular_componentNuA4 histone acetyltransferase complex
F0043138molecular_function3'-5' DNA helicase activity
F0043139molecular_function5'-3' DNA helicase activity
F0050821biological_processprotein stabilization
F0097255cellular_componentR2TP complex
F0110078cellular_componentTTT Hsp90 cochaperone complex
G0000166molecular_functionnucleotide binding
G0000492biological_processbox C/D snoRNP assembly
G0000785cellular_componentchromatin
G0000812cellular_componentSwr1 complex
G0003678molecular_functionDNA helicase activity
G0004386molecular_functionhelicase activity
G0005515molecular_functionprotein binding
G0005524molecular_functionATP binding
G0005634cellular_componentnucleus
G0006281biological_processDNA repair
G0006325biological_processchromatin organization
G0006338biological_processchromatin remodeling
G0006355biological_processregulation of DNA-templated transcription
G0006357biological_processregulation of transcription by RNA polymerase II
G0006974biological_processDNA damage response
G0008094molecular_functionATP-dependent activity, acting on DNA
G0008643biological_processcarbohydrate transport
G0015144molecular_functioncarbohydrate transmembrane transporter activity
G0016787molecular_functionhydrolase activity
G0016887molecular_functionATP hydrolysis activity
G0031011cellular_componentIno80 complex
G0035267cellular_componentNuA4 histone acetyltransferase complex
G0043138molecular_function3'-5' DNA helicase activity
G0043139molecular_function5'-3' DNA helicase activity
G0050821biological_processprotein stabilization
G0055085biological_processtransmembrane transport
G0097255cellular_componentR2TP complex
G0110078cellular_componentTTT Hsp90 cochaperone complex
H0000166molecular_functionnucleotide binding
H0000492biological_processbox C/D snoRNP assembly
H0000785cellular_componentchromatin
H0000812cellular_componentSwr1 complex
H0003678molecular_functionDNA helicase activity
H0004386molecular_functionhelicase activity
H0005515molecular_functionprotein binding
H0005524molecular_functionATP binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0006281biological_processDNA repair
H0006325biological_processchromatin organization
H0006338biological_processchromatin remodeling
H0006355biological_processregulation of DNA-templated transcription
H0006357biological_processregulation of transcription by RNA polymerase II
H0006364biological_processrRNA processing
H0006974biological_processDNA damage response
H0008094molecular_functionATP-dependent activity, acting on DNA
H0016787molecular_functionhydrolase activity
H0016887molecular_functionATP hydrolysis activity
H0031011cellular_componentIno80 complex
H0035267cellular_componentNuA4 histone acetyltransferase complex
H0043138molecular_function3'-5' DNA helicase activity
H0043139molecular_function5'-3' DNA helicase activity
H0050821biological_processprotein stabilization
H0097255cellular_componentR2TP complex
H0110078cellular_componentTTT Hsp90 cochaperone complex
I0000166molecular_functionnucleotide binding
I0000492biological_processbox C/D snoRNP assembly
I0000785cellular_componentchromatin
I0000812cellular_componentSwr1 complex
I0003678molecular_functionDNA helicase activity
I0004386molecular_functionhelicase activity
I0005515molecular_functionprotein binding
I0005524molecular_functionATP binding
I0005634cellular_componentnucleus
I0006281biological_processDNA repair
I0006325biological_processchromatin organization
I0006338biological_processchromatin remodeling
I0006355biological_processregulation of DNA-templated transcription
I0006357biological_processregulation of transcription by RNA polymerase II
I0006974biological_processDNA damage response
I0008094molecular_functionATP-dependent activity, acting on DNA
I0008643biological_processcarbohydrate transport
I0015144molecular_functioncarbohydrate transmembrane transporter activity
I0016787molecular_functionhydrolase activity
I0016887molecular_functionATP hydrolysis activity
I0031011cellular_componentIno80 complex
I0035267cellular_componentNuA4 histone acetyltransferase complex
I0043138molecular_function3'-5' DNA helicase activity
I0043139molecular_function5'-3' DNA helicase activity
I0050821biological_processprotein stabilization
I0055085biological_processtransmembrane transport
I0097255cellular_componentR2TP complex
I0110078cellular_componentTTT Hsp90 cochaperone complex
J0000166molecular_functionnucleotide binding
J0000492biological_processbox C/D snoRNP assembly
J0000785cellular_componentchromatin
J0000812cellular_componentSwr1 complex
J0003678molecular_functionDNA helicase activity
J0004386molecular_functionhelicase activity
J0005515molecular_functionprotein binding
J0005524molecular_functionATP binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0006281biological_processDNA repair
J0006325biological_processchromatin organization
J0006338biological_processchromatin remodeling
J0006355biological_processregulation of DNA-templated transcription
J0006357biological_processregulation of transcription by RNA polymerase II
J0006364biological_processrRNA processing
J0006974biological_processDNA damage response
J0008094molecular_functionATP-dependent activity, acting on DNA
J0016787molecular_functionhydrolase activity
J0016887molecular_functionATP hydrolysis activity
J0031011cellular_componentIno80 complex
J0035267cellular_componentNuA4 histone acetyltransferase complex
J0043138molecular_function3'-5' DNA helicase activity
J0043139molecular_function5'-3' DNA helicase activity
J0050821biological_processprotein stabilization
J0097255cellular_componentR2TP complex
J0110078cellular_componentTTT Hsp90 cochaperone complex
Functional Information from PROSITE/UniProt
site_idPS01037
Number of Residues18
DetailsSBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN
ChainResidueDetails
EPRO577-ASN594

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
EGLY79
GGLY79
IGLY79

site_idSWS_FT_FI2
Number of Residues3
DetailsMOD_RES: N-acetylvaline => ECO:0000269|PubMed:15525518
ChainResidueDetails
EVAL2
GVAL2
IVAL2
DCYS259
DCYS264
DCYS268
DHIS272
DCYS277

237992

PDB entries from 2025-06-25

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