8ZYR
Cryo-EM structure of BTN2A1-BTN3A1-BTN3A3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001817 | biological_process | regulation of cytokine production |
| A | 0005102 | molecular_function | signaling receptor binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0009897 | cellular_component | external side of plasma membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0050852 | biological_process | T cell receptor signaling pathway |
| B | 0001817 | biological_process | regulation of cytokine production |
| B | 0001819 | biological_process | positive regulation of cytokine production |
| B | 0002250 | biological_process | adaptive immune response |
| B | 0002376 | biological_process | immune system process |
| B | 0005102 | molecular_function | signaling receptor binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0009897 | cellular_component | external side of plasma membrane |
| B | 0032729 | biological_process | positive regulation of type II interferon production |
| B | 0050798 | biological_process | activated T cell proliferation |
| B | 0050852 | biological_process | T cell receptor signaling pathway |
| C | 0001817 | biological_process | regulation of cytokine production |
| C | 0002250 | biological_process | adaptive immune response |
| C | 0002376 | biological_process | immune system process |
| C | 0002456 | biological_process | T cell mediated immunity |
| C | 0005102 | molecular_function | signaling receptor binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009897 | cellular_component | external side of plasma membrane |
| C | 0016020 | cellular_component | membrane |
| C | 0050852 | biological_process | T cell receptor signaling pathway |
| D | 0001817 | biological_process | regulation of cytokine production |
| D | 0005102 | molecular_function | signaling receptor binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0009897 | cellular_component | external side of plasma membrane |
| D | 0016020 | cellular_component | membrane |
| D | 0050852 | biological_process | T cell receptor signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 880 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 76 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 224 |
| Details | Domain: {"description":"Ig-like V-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 583 |
| Details | Domain: {"description":"B30.2/SPRY","evidences":[{"source":"PROSITE-ProRule","id":"PRU00548","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 241 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 218 |
| Details | Domain: {"description":"Ig-like V-type 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 182 |
| Details | Domain: {"description":"Ig-like V-type 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22846996","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
