8ZWK
Polyadenylic acid bound alpha-synuclein fibril Polymorph 2
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | ASP2 | |
| C | HIS50 | |
| F | ASP2 | |
| F | HIS50 | |
| A | HIS50 | |
| D | ASP2 | |
| D | HIS50 | |
| E | ASP2 | |
| E | HIS50 | |
| B | ASP2 | |
| B | HIS50 | |
| C | ASP2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | MOD_RES: N-acetylmethionine => ECO:0000269|PubMed:22407793 |
| Chain | Residue | Details |
| A | MET1 | |
| D | MET1 | |
| E | MET1 | |
| B | MET1 | |
| C | MET1 | |
| F | MET1 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:10617630 |
| Chain | Residue | Details |
| A | SER87 | |
| D | SER87 | |
| E | SER87 | |
| B | SER87 | |
| C | SER87 | |
| F | SER87 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphotyrosine; by FYN => ECO:0000269|PubMed:11162638, ECO:0000269|PubMed:12893833 |
| Chain | Residue | Details |
| A | TYR125 | |
| D | TYR125 | |
| E | TYR125 | |
| B | TYR125 | |
| C | TYR125 | |
| F | TYR125 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine; by BARK1, PLK2, CK2, CK1 and GRK5 => ECO:0000269|PubMed:10617630, ECO:0000269|PubMed:11813001, ECO:0000269|PubMed:24936070 |
| Chain | Residue | Details |
| A | SER129 | |
| D | SER129 | |
| E | SER129 | |
| B | SER129 | |
| C | SER129 | |
| F | SER129 |
