8ZVL

human citrate synthases complexed with oxaloacetate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0005634	cellular_component	nucleus
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0005975	biological_process	carbohydrate metabolic process
A	0006099	biological_process	tricarboxylic acid cycle
A	0006101	biological_process	citrate metabolic process
A	0016740	molecular_function	transferase activity
A	0036440	molecular_function	citrate synthase activity
A	0042802	molecular_function	identical protein binding
A	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
A	0070062	cellular_component	extracellular exosome
B	0003723	molecular_function	RNA binding
B	0005634	cellular_component	nucleus
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0005975	biological_process	carbohydrate metabolic process
B	0006099	biological_process	tricarboxylic acid cycle
B	0006101	biological_process	citrate metabolic process
B	0016740	molecular_function	transferase activity
B	0036440	molecular_function	citrate synthase activity
B	0042802	molecular_function	identical protein binding
B	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
B	0070062	cellular_component	extracellular exosome
C	0003723	molecular_function	RNA binding
C	0005634	cellular_component	nucleus
C	0005739	cellular_component	mitochondrion
C	0005759	cellular_component	mitochondrial matrix
C	0005975	biological_process	carbohydrate metabolic process
C	0006099	biological_process	tricarboxylic acid cycle
C	0006101	biological_process	citrate metabolic process
C	0016740	molecular_function	transferase activity
C	0036440	molecular_function	citrate synthase activity
C	0042802	molecular_function	identical protein binding
C	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
C	0070062	cellular_component	extracellular exosome
D	0003723	molecular_function	RNA binding
D	0005634	cellular_component	nucleus
D	0005739	cellular_component	mitochondrion
D	0005759	cellular_component	mitochondrial matrix
D	0005975	biological_process	carbohydrate metabolic process
D	0006099	biological_process	tricarboxylic acid cycle
D	0006101	biological_process	citrate metabolic process
D	0016740	molecular_function	transferase activity
D	0036440	molecular_function	citrate synthase activity
D	0042802	molecular_function	identical protein binding
D	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
D	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00480
Number of Residues	13
Details	CITRATE_SYNTHASE Citrate synthase signature. GYGHaVl.RktDPR

Chain	Residue	Details
A	GLY344-ARG356

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10117","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"description":"in chain A","evidences":[{"source":"PubMed","id":"31141475","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5UZP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"description":"in chain B","evidences":[{"source":"PubMed","id":"31141475","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5UZP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q9CZU6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q29RK1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	20
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9CZU6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"source":"PubMed","id":"28391595","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28887308","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---