8ZTC

Crystal structure of Mps1-AMP complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000196	biological_process	cell integrity MAPK cascade
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0004707	molecular_function	MAP kinase activity
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006950	biological_process	response to stress
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0032995	biological_process	regulation of fungal-type cell wall biogenesis
A	0050850	biological_process	positive regulation of calcium-mediated signaling
A	0051094	biological_process	positive regulation of developmental process
A	1902413	biological_process	negative regulation of mitotic cytokinesis
A	1902660	biological_process	negative regulation of glucose mediated signaling pathway
A	1905665	biological_process	positive regulation of calcium ion import across plasma membrane

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	25
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGQGAYGIVCaAvnnqtsegv.........AIKK

Chain	Residue	Details
A	LEU29-LYS53

---

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpgNLLV

Chain	Residue	Details
A	VAL145-VAL157

---

site_id	PS01351
Number of Residues	104
Details	MAPK MAP kinase signature. FskkilakralREikllqhfrghrnitclydmdiprpdnfnetylyeelmecdlaaiirsgqpltdahfqsfiyqilcglkyihsanvlh.........RDlKpgnllvnadC

Chain	Residue	Details
A	PHE58-CYS161

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	LEU29
A	LYS52

---