8ZSB
Cryo-EM structure of human ZnT1, in the absence of zinc, determined in outward-facing conformation
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 640 |
Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:31471319 |
Chain | Residue | Details |
A | MET1-ARG10 | |
A | ALA57-GLU78 | |
A | HIS135-VAL248 | |
A | TYR330-LEU507 | |
B | MET1-ARG10 | |
B | ALA57-GLU78 | |
B | HIS135-VAL248 | |
B | TYR330-LEU507 |
site_id | SWS_FT_FI2 |
Number of Residues | 240 |
Details | TRANSMEM: Helical => ECO:0000255 |
Chain | Residue | Details |
A | LEU11-VAL31 | |
B | LEU114-PHE134 | |
B | PHE249-PHE269 | |
B | GLY309-LEU329 | |
A | ALA36-VAL56 | |
A | VAL79-GLU99 | |
A | LEU114-PHE134 | |
A | PHE249-PHE269 | |
A | GLY309-LEU329 | |
B | LEU11-VAL31 | |
B | ALA36-VAL56 | |
B | VAL79-GLU99 |
site_id | SWS_FT_FI3 |
Number of Residues | 108 |
Details | TOPO_DOM: Extracellular => ECO:0000305|PubMed:31471319 |
Chain | Residue | Details |
A | THR32-LEU35 | |
A | ALA100-PRO113 | |
A | TYR270-ALA308 | |
B | THR32-LEU35 | |
B | ALA100-PRO113 | |
B | TYR270-ALA308 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q62720 |
Chain | Residue | Details |
A | HIS43 | |
A | ASP255 | |
B | HIS43 | |
B | ASP255 |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:P69380 |
Chain | Residue | Details |
A | ASP47 | |
A | HIS251 | |
B | ASP47 | |
B | HIS251 |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648 |
Chain | Residue | Details |
A | SER506 | |
B | SER506 |
site_id | SWS_FT_FI7 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:31471319 |
Chain | Residue | Details |
A | ASN299 | |
B | ASN299 |