8ZMD
Protease-activated receptor-2 (PAR2)/Gq complex
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS |
| Chain | Residue | Details |
| B | LEU70-SER84 | |
| B | ILE157-ILE171 | |
| B | LEU285-ALA299 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 73 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:28445455 |
| Chain | Residue | Details |
| R | SER37-GLY71 | |
| R | GLY138-ASN149 | |
| R | VAL212-LEU235 | |
| R | GLY318-TYR323 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 29 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:28445455 |
| Chain | Residue | Details |
| R | LYS72-LEU101 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 67 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:28445455 |
| Chain | Residue | Details |
| R | PHE102-HIS108 | |
| R | VAL178-HIS183 | |
| R | ARG270-ASN277 | |
| R | SER348-TYR397 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 28 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:28445455 |
| Chain | Residue | Details |
| R | PRO109-HIS137 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 27 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:28445455 |
| Chain | Residue | Details |
| R | VAL150-ILE177 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 27 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:28445455 |
| Chain | Residue | Details |
| R | SER184-VAL211 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 33 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:28445455 |
| Chain | Residue | Details |
| R | VAL236-LEU269 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 39 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:28445455 |
| Chain | Residue | Details |
| R | SER278-GLN317 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000269|PubMed:28445455 |
| Chain | Residue | Details |
| R | ALA324-VAL347 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by trypsin |
| Chain | Residue | Details |
| R | ARG36 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:21627585 |
| Chain | Residue | Details |
| R | CYS361 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12171601 |
| Chain | Residue | Details |
| R | ASN30 | |
| R | ASN222 |
