Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8ZIX

RAT skeletal muscle F-actin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001725	cellular_component	stress fiber
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005856	cellular_component	cytoskeleton
A	0005865	cellular_component	striated muscle thin filament
A	0005884	cellular_component	actin filament
A	0009612	biological_process	response to mechanical stimulus
A	0010628	biological_process	positive regulation of gene expression
A	0015629	cellular_component	actin cytoskeleton
A	0016787	molecular_function	hydrolase activity
A	0030017	cellular_component	sarcomere
A	0030027	cellular_component	lamellipodium
A	0030175	cellular_component	filopodium
A	0030240	biological_process	skeletal muscle thin filament assembly
A	0035865	biological_process	cellular response to potassium ion
A	0043503	biological_process	skeletal muscle fiber adaptation
A	0044297	cellular_component	cell body
A	0048545	biological_process	response to steroid hormone
A	0048741	biological_process	skeletal muscle fiber development
A	0090131	biological_process	mesenchyme migration
B	0000166	molecular_function	nucleotide binding
B	0001725	cellular_component	stress fiber
B	0005200	molecular_function	structural constituent of cytoskeleton
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005856	cellular_component	cytoskeleton
B	0005865	cellular_component	striated muscle thin filament
B	0005884	cellular_component	actin filament
B	0009612	biological_process	response to mechanical stimulus
B	0010628	biological_process	positive regulation of gene expression
B	0015629	cellular_component	actin cytoskeleton
B	0016787	molecular_function	hydrolase activity
B	0030017	cellular_component	sarcomere
B	0030027	cellular_component	lamellipodium
B	0030175	cellular_component	filopodium
B	0030240	biological_process	skeletal muscle thin filament assembly
B	0035865	biological_process	cellular response to potassium ion
B	0043503	biological_process	skeletal muscle fiber adaptation
B	0044297	cellular_component	cell body
B	0048545	biological_process	response to steroid hormone
B	0048741	biological_process	skeletal muscle fiber development
B	0090131	biological_process	mesenchyme migration
E	0000166	molecular_function	nucleotide binding
E	0001725	cellular_component	stress fiber
E	0005200	molecular_function	structural constituent of cytoskeleton
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005856	cellular_component	cytoskeleton
E	0005865	cellular_component	striated muscle thin filament
E	0005884	cellular_component	actin filament
E	0009612	biological_process	response to mechanical stimulus
E	0010628	biological_process	positive regulation of gene expression
E	0015629	cellular_component	actin cytoskeleton
E	0016787	molecular_function	hydrolase activity
E	0030017	cellular_component	sarcomere
E	0030027	cellular_component	lamellipodium
E	0030175	cellular_component	filopodium
E	0030240	biological_process	skeletal muscle thin filament assembly
E	0035865	biological_process	cellular response to potassium ion
E	0043503	biological_process	skeletal muscle fiber adaptation
E	0044297	cellular_component	cell body
E	0048545	biological_process	response to steroid hormone
E	0048741	biological_process	skeletal muscle fiber development
E	0090131	biological_process	mesenchyme migration
F	0000166	molecular_function	nucleotide binding
F	0001725	cellular_component	stress fiber
F	0005200	molecular_function	structural constituent of cytoskeleton
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005856	cellular_component	cytoskeleton
F	0005865	cellular_component	striated muscle thin filament
F	0005884	cellular_component	actin filament
F	0009612	biological_process	response to mechanical stimulus
F	0010628	biological_process	positive regulation of gene expression
F	0015629	cellular_component	actin cytoskeleton
F	0016787	molecular_function	hydrolase activity
F	0030017	cellular_component	sarcomere
F	0030027	cellular_component	lamellipodium
F	0030175	cellular_component	filopodium
F	0030240	biological_process	skeletal muscle thin filament assembly
F	0035865	biological_process	cellular response to potassium ion
F	0043503	biological_process	skeletal muscle fiber adaptation
F	0044297	cellular_component	cell body
F	0048545	biological_process	response to steroid hormone
F	0048741	biological_process	skeletal muscle fiber development
F	0090131	biological_process	mesenchyme migration
P	0000166	molecular_function	nucleotide binding
P	0001725	cellular_component	stress fiber
P	0005200	molecular_function	structural constituent of cytoskeleton
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005856	cellular_component	cytoskeleton
P	0005865	cellular_component	striated muscle thin filament
P	0005884	cellular_component	actin filament
P	0009612	biological_process	response to mechanical stimulus
P	0010628	biological_process	positive regulation of gene expression
P	0015629	cellular_component	actin cytoskeleton
P	0016787	molecular_function	hydrolase activity
P	0030017	cellular_component	sarcomere
P	0030027	cellular_component	lamellipodium
P	0030175	cellular_component	filopodium
P	0030240	biological_process	skeletal muscle thin filament assembly
P	0035865	biological_process	cellular response to potassium ion
P	0043503	biological_process	skeletal muscle fiber adaptation
P	0044297	cellular_component	cell body
P	0048545	biological_process	response to steroid hormone
P	0048741	biological_process	skeletal muscle fiber development
P	0090131	biological_process	mesenchyme migration
R	0000166	molecular_function	nucleotide binding
R	0001725	cellular_component	stress fiber
R	0005200	molecular_function	structural constituent of cytoskeleton
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0005856	cellular_component	cytoskeleton
R	0005865	cellular_component	striated muscle thin filament
R	0005884	cellular_component	actin filament
R	0009612	biological_process	response to mechanical stimulus
R	0010628	biological_process	positive regulation of gene expression
R	0015629	cellular_component	actin cytoskeleton
R	0016787	molecular_function	hydrolase activity
R	0030017	cellular_component	sarcomere
R	0030027	cellular_component	lamellipodium
R	0030175	cellular_component	filopodium
R	0030240	biological_process	skeletal muscle thin filament assembly
R	0035865	biological_process	cellular response to potassium ion
R	0043503	biological_process	skeletal muscle fiber adaptation
R	0044297	cellular_component	cell body
R	0048545	biological_process	response to steroid hormone
R	0048741	biological_process	skeletal muscle fiber development
R	0090131	biological_process	mesenchyme migration

Functional Information from PROSITE/UniProt

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
P	TYR55-GLY65

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WITKqEYDE

Chain	Residue	Details
P	TRP358-GLU366

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
P	LEU106-ARG118

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	150
Details	Region: {"description":"Interaction with alpha-actinin","evidences":[{"source":"UniProtKB","id":"P68135","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	12
Details	Modified residue: {"description":"Methionine (R)-sulfoxide","evidences":[{"source":"UniProtKB","id":"P68134","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	6
Details	Modified residue: {"description":"N6-malonyllysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	6
Details	Modified residue: {"description":"Tele-methylhistidine","evidences":[{"source":"UniProtKB","id":"P68138","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	6
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"UniProtKB","id":"P68133","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)