8ZHR
Cryo-EM structure of the full-length pAg-bound BTN2A1-BTN3A1-BTN3A2 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001817 | biological_process | regulation of cytokine production |
| A | 0005102 | molecular_function | signaling receptor binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0009897 | cellular_component | external side of plasma membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0050852 | biological_process | T cell receptor signaling pathway |
| B | 0001817 | biological_process | regulation of cytokine production |
| B | 0005102 | molecular_function | signaling receptor binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0009897 | cellular_component | external side of plasma membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0050852 | biological_process | T cell receptor signaling pathway |
| E | 0001817 | biological_process | regulation of cytokine production |
| E | 0002250 | biological_process | adaptive immune response |
| E | 0002376 | biological_process | immune system process |
| E | 0002456 | biological_process | T cell mediated immunity |
| E | 0005102 | molecular_function | signaling receptor binding |
| E | 0005515 | molecular_function | protein binding |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0009897 | cellular_component | external side of plasma membrane |
| E | 0016020 | cellular_component | membrane |
| E | 0032729 | biological_process | positive regulation of type II interferon production |
| E | 0050852 | biological_process | T cell receptor signaling pathway |
| F | 0001817 | biological_process | regulation of cytokine production |
| F | 0001819 | biological_process | positive regulation of cytokine production |
| F | 0002250 | biological_process | adaptive immune response |
| F | 0002376 | biological_process | immune system process |
| F | 0005102 | molecular_function | signaling receptor binding |
| F | 0005515 | molecular_function | protein binding |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0009897 | cellular_component | external side of plasma membrane |
| F | 0032729 | biological_process | positive regulation of type II interferon production |
| F | 0050798 | biological_process | activated T cell proliferation |
| F | 0050852 | biological_process | T cell receptor signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 880 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 76 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 333 |
| Details | Domain: {"description":"Ig-like V-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 47 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 583 |
| Details | Domain: {"description":"B30.2/SPRY","evidences":[{"source":"PROSITE-ProRule","id":"PRU00548","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 241 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 109 |
| Details | Domain: {"description":"Ig-like V-type 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 91 |
| Details | Domain: {"description":"Ig-like V-type 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22846996","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
