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8ZEQ

Molecular Architecture of Human Glycogen Debranching Enzyme: Insights into Glycogen Storage Disease III Pathogenesis

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0004134molecular_function4-alpha-glucanotransferase activity
A0004135molecular_functionamylo-alpha-1,6-glucosidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005975biological_processcarbohydrate metabolic process
A0005978biological_processglycogen biosynthetic process
A0005980biological_processglycogen catabolic process
A0007584biological_processresponse to nutrient
A0009725biological_processresponse to hormone
A0016234cellular_componentinclusion body
A0016529cellular_componentsarcoplasmic reticulum
A0016604cellular_componentnuclear body
A0016740molecular_functiontransferase activity
A0016757molecular_functionglycosyltransferase activity
A0016787molecular_functionhydrolase activity
A0016798molecular_functionhydrolase activity, acting on glycosyl bonds
A0030246molecular_functioncarbohydrate binding
A0030247molecular_functionpolysaccharide binding
A0031593molecular_functionpolyubiquitin modification-dependent protein binding
A0034774cellular_componentsecretory granule lumen
A0043033cellular_componentisoamylase complex
A0051384biological_processresponse to glucocorticoid
A1904813cellular_componentficolin-1-rich granule lumen
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsRegion: {"description":"4-alpha-glucanotransferase"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues3
DetailsActive site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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