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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8ZAL

EmrAB-TolC MFS-type tripartite multidrug efflux pump EA

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0042910molecular_functionxenobiotic transmembrane transporter activity
A1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
B0042910molecular_functionxenobiotic transmembrane transporter activity
B1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
C0042910molecular_functionxenobiotic transmembrane transporter activity
C1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
D0042910molecular_functionxenobiotic transmembrane transporter activity
D1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
E0042910molecular_functionxenobiotic transmembrane transporter activity
E1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
F0042910molecular_functionxenobiotic transmembrane transporter activity
F1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
G0005216molecular_functionmonoatomic ion channel activity
G0005515molecular_functionprotein binding
G0009279cellular_componentcell outer membrane
G0009410biological_processresponse to xenobiotic stimulus
G0009636biological_processresponse to toxic substance
G0015125molecular_functionbile acid transmembrane transporter activity
G0015288molecular_functionporin activity
G0015562molecular_functionefflux transmembrane transporter activity
G0015721biological_processbile acid and bile salt transport
G0016020cellular_componentmembrane
G0019867cellular_componentouter membrane
G0034220biological_processmonoatomic ion transmembrane transport
G0042802molecular_functionidentical protein binding
G0042930biological_processenterobactin transport
G0042931molecular_functionenterobactin transmembrane transporter activity
G0046677biological_processresponse to antibiotic
G0055085biological_processtransmembrane transport
G0098567cellular_componentperiplasmic side of plasma membrane
G0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
G1990196cellular_componentMacAB-TolC complex
G1990281cellular_componentefflux pump complex
G1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
H0005216molecular_functionmonoatomic ion channel activity
H0005515molecular_functionprotein binding
H0009279cellular_componentcell outer membrane
H0009410biological_processresponse to xenobiotic stimulus
H0009636biological_processresponse to toxic substance
H0015125molecular_functionbile acid transmembrane transporter activity
H0015288molecular_functionporin activity
H0015562molecular_functionefflux transmembrane transporter activity
H0015721biological_processbile acid and bile salt transport
H0016020cellular_componentmembrane
H0019867cellular_componentouter membrane
H0034220biological_processmonoatomic ion transmembrane transport
H0042802molecular_functionidentical protein binding
H0042930biological_processenterobactin transport
H0042931molecular_functionenterobactin transmembrane transporter activity
H0046677biological_processresponse to antibiotic
H0055085biological_processtransmembrane transport
H0098567cellular_componentperiplasmic side of plasma membrane
H0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
H1990196cellular_componentMacAB-TolC complex
H1990281cellular_componentefflux pump complex
H1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
I0005216molecular_functionmonoatomic ion channel activity
I0005515molecular_functionprotein binding
I0009279cellular_componentcell outer membrane
I0009410biological_processresponse to xenobiotic stimulus
I0009636biological_processresponse to toxic substance
I0015125molecular_functionbile acid transmembrane transporter activity
I0015288molecular_functionporin activity
I0015562molecular_functionefflux transmembrane transporter activity
I0015721biological_processbile acid and bile salt transport
I0016020cellular_componentmembrane
I0019867cellular_componentouter membrane
I0034220biological_processmonoatomic ion transmembrane transport
I0042802molecular_functionidentical protein binding
I0042930biological_processenterobactin transport
I0042931molecular_functionenterobactin transmembrane transporter activity
I0046677biological_processresponse to antibiotic
I0055085biological_processtransmembrane transport
I0098567cellular_componentperiplasmic side of plasma membrane
I0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
I1990196cellular_componentMacAB-TolC complex
I1990281cellular_componentefflux pump complex
I1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
J0005515molecular_functionprotein binding
J0005886cellular_componentplasma membrane
J0009636biological_processresponse to toxic substance
J0015125molecular_functionbile acid transmembrane transporter activity
J0015721biological_processbile acid and bile salt transport
J0016020cellular_componentmembrane
J0022857molecular_functiontransmembrane transporter activity
J0046677biological_processresponse to antibiotic
J0048545biological_processresponse to steroid hormone
J0055085biological_processtransmembrane transport
J0098567cellular_componentperiplasmic side of plasma membrane
J0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
J1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues360
DetailsCoiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues630
DetailsTopological domain: {"description":"Periplasmic"}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues33
DetailsTransmembrane: {"description":"Beta stranded; Name=S1"}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues81
DetailsTopological domain: {"description":"Extracellular"}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues39
DetailsTransmembrane: {"description":"Beta stranded; Name=S2"}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues30
DetailsTransmembrane: {"description":"Beta stranded; Name=S4"}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues30
DetailsTransmembrane: {"description":"Beta stranded; Name=S5"}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues621
DetailsRepeat: {"description":"1"}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues645
DetailsRepeat: {"description":"2"}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues84
DetailsRegion: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues45
DetailsCompositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues270
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues101
DetailsTopological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues72
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

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PDB entries from 2026-01-28

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