8YTC
PML-RBCC dimer
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. ClHtLCsgCL |
| Chain | Residue | Details |
| A | CYS72-LEU81 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 70 |
| Details | ZN_FING: RING-type => ECO:0000255|PROSITE-ProRule:PRU00175 |
| Chain | Residue | Details |
| A | CYS57-GLN92 | |
| B | CYS57-GLN92 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 84 |
| Details | ZN_FING: B box-type 1; atypical => ECO:0000255|PROSITE-ProRule:PRU00024 |
| Chain | Residue | Details |
| A | ASP124-LEU166 | |
| B | ASP124-LEU166 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 106 |
| Details | ZN_FING: B box-type 2 => ECO:0000255|PROSITE-ProRule:PRU00024 |
| Chain | Residue | Details |
| A | LYS183-ARG236 | |
| B | LYS183-ARG236 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | CYS57 | |
| B | CYS60 | |
| B | CYS72 | |
| B | HIS74 | |
| B | CYS77 | |
| B | CYS80 | |
| B | CYS88 | |
| B | CYS91 | |
| A | CYS60 | |
| A | CYS72 | |
| A | HIS74 | |
| A | CYS77 | |
| A | CYS80 | |
| A | CYS88 | |
| A | CYS91 | |
| B | CYS57 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00024 |
| Chain | Residue | Details |
| A | CYS129 | |
| B | CYS132 | |
| B | CYS151 | |
| B | HIS155 | |
| B | CYS189 | |
| B | HIS194 | |
| B | CYS215 | |
| B | HIS222 | |
| A | CYS132 | |
| A | CYS151 | |
| A | HIS155 | |
| A | CYS189 | |
| A | HIS194 | |
| A | CYS215 | |
| A | HIS222 | |
| B | CYS129 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER48 | |
| B | SER48 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by CHEK2 => ECO:0000269|PubMed:12402044 |
| Chain | Residue | Details |
| A | SER117 | |
| B | SER117 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS65 | |
| B | LYS65 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS160 | |
| B | LYS160 |
