8YR5

Crystal structure of E. coli phosphatidylserine synthase in apo state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
A	0005515	molecular_function	protein binding
A	0005543	molecular_function	phospholipid binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0006793	biological_process	phosphorus metabolic process
A	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
A	0008654	biological_process	phospholipid biosynthetic process
A	0016740	molecular_function	transferase activity
A	0032049	biological_process	cardiolipin biosynthetic process
B	0003824	molecular_function	catalytic activity
B	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
B	0005515	molecular_function	protein binding
B	0005543	molecular_function	phospholipid binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006629	biological_process	lipid metabolic process
B	0006793	biological_process	phosphorus metabolic process
B	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
B	0008654	biological_process	phospholipid biosynthetic process
B	0016740	molecular_function	transferase activity
B	0032049	biological_process	cardiolipin biosynthetic process
C	0003824	molecular_function	catalytic activity
C	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
C	0005515	molecular_function	protein binding
C	0005543	molecular_function	phospholipid binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006629	biological_process	lipid metabolic process
C	0006793	biological_process	phosphorus metabolic process
C	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
C	0008654	biological_process	phospholipid biosynthetic process
C	0016740	molecular_function	transferase activity
C	0032049	biological_process	cardiolipin biosynthetic process
D	0003824	molecular_function	catalytic activity
D	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
D	0005515	molecular_function	protein binding
D	0005543	molecular_function	phospholipid binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006629	biological_process	lipid metabolic process
D	0006793	biological_process	phosphorus metabolic process
D	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
D	0008654	biological_process	phospholipid biosynthetic process
D	0016740	molecular_function	transferase activity
D	0032049	biological_process	cardiolipin biosynthetic process
E	0003824	molecular_function	catalytic activity
E	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
E	0005515	molecular_function	protein binding
E	0005543	molecular_function	phospholipid binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006629	biological_process	lipid metabolic process
E	0006793	biological_process	phosphorus metabolic process
E	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
E	0008654	biological_process	phospholipid biosynthetic process
E	0016740	molecular_function	transferase activity
E	0032049	biological_process	cardiolipin biosynthetic process
F	0003824	molecular_function	catalytic activity
F	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
F	0005515	molecular_function	protein binding
F	0005543	molecular_function	phospholipid binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006629	biological_process	lipid metabolic process
F	0006793	biological_process	phosphorus metabolic process
F	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
F	0008654	biological_process	phospholipid biosynthetic process
F	0016740	molecular_function	transferase activity
F	0032049	biological_process	cardiolipin biosynthetic process
G	0003824	molecular_function	catalytic activity
G	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
G	0005515	molecular_function	protein binding
G	0005543	molecular_function	phospholipid binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0006629	biological_process	lipid metabolic process
G	0006793	biological_process	phosphorus metabolic process
G	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
G	0008654	biological_process	phospholipid biosynthetic process
G	0016740	molecular_function	transferase activity
G	0032049	biological_process	cardiolipin biosynthetic process
H	0003824	molecular_function	catalytic activity
H	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
H	0005515	molecular_function	protein binding
H	0005543	molecular_function	phospholipid binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006629	biological_process	lipid metabolic process
H	0006793	biological_process	phosphorus metabolic process
H	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
H	0008654	biological_process	phospholipid biosynthetic process
H	0016740	molecular_function	transferase activity
H	0032049	biological_process	cardiolipin biosynthetic process
I	0003824	molecular_function	catalytic activity
I	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
I	0005515	molecular_function	protein binding
I	0005543	molecular_function	phospholipid binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0006629	biological_process	lipid metabolic process
I	0006793	biological_process	phosphorus metabolic process
I	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
I	0008654	biological_process	phospholipid biosynthetic process
I	0016740	molecular_function	transferase activity
I	0032049	biological_process	cardiolipin biosynthetic process
J	0003824	molecular_function	catalytic activity
J	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
J	0005515	molecular_function	protein binding
J	0005543	molecular_function	phospholipid binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0006629	biological_process	lipid metabolic process
J	0006793	biological_process	phosphorus metabolic process
J	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
J	0008654	biological_process	phospholipid biosynthetic process
J	0016740	molecular_function	transferase activity
J	0032049	biological_process	cardiolipin biosynthetic process
K	0003824	molecular_function	catalytic activity
K	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
K	0005515	molecular_function	protein binding
K	0005543	molecular_function	phospholipid binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0006629	biological_process	lipid metabolic process
K	0006793	biological_process	phosphorus metabolic process
K	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
K	0008654	biological_process	phospholipid biosynthetic process
K	0016740	molecular_function	transferase activity
K	0032049	biological_process	cardiolipin biosynthetic process
L	0003824	molecular_function	catalytic activity
L	0003882	molecular_function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity
L	0005515	molecular_function	protein binding
L	0005543	molecular_function	phospholipid binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0006629	biological_process	lipid metabolic process
L	0006793	biological_process	phosphorus metabolic process
L	0008444	molecular_function	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
L	0008654	biological_process	phospholipid biosynthetic process
L	0016740	molecular_function	transferase activity
L	0032049	biological_process	cardiolipin biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2544
Details	Domain: {"description":"PLD phosphodiesterase 2","evidences":[{"source":"PubMed","id":"39693441","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00153","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"39693441","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Active site: {"evidences":[{"source":"PubMed","id":"39693441","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	336
Details	Binding site: {"evidences":[{"source":"PubMed","id":"39693441","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8YR6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	591
Details	Domain: {"description":"PLD phosphodiesterase 1","evidences":[{"source":"PubMed","id":"39693441","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---