8YR4
Cryo-EM structure of the human ABCB6 in complex with Cd(II):Phytochelatin 2
Functional Information from PROSITE/UniProt
| site_id | PS00211 |
| Number of Residues | 15 |
| Details | ABC_TRANSPORTER_1 ABC transporters family signature. LSGGEKQRVAIARTI |
| Chain | Residue | Details |
| A | LEU727-ILE741 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 978 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | PRO207-LEU263 | |
| A | LYS313-ARG375 | |
| A | LEU419-GLN499 | |
| A | TYR551-ARG842 | |
| B | PRO207-LEU263 | |
| B | LYS313-ARG375 | |
| B | LEU419-GLN499 | |
| B | TYR551-ARG842 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 240 |
| Details | TRANSMEM: Helical => ECO:0000255, ECO:0000255|PROSITE-ProRule:PRU00441 |
| Chain | Residue | Details |
| A | VAL264-ILE284 | |
| B | ILE398-PHE418 | |
| B | THR500-VAL520 | |
| B | TYR530-TYR550 | |
| A | LEU292-LEU312 | |
| A | GLY376-ALA396 | |
| A | ILE398-PHE418 | |
| A | THR500-VAL520 | |
| A | TYR530-TYR550 | |
| B | VAL264-ILE284 | |
| B | LEU292-LEU312 | |
| B | GLY376-ALA396 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | TOPO_DOM: Lumenal => ECO:0000305|PubMed:18279659, ECO:0000305|PubMed:21199866 |
| Chain | Residue | Details |
| A | PHE285-ASN291 | |
| A | ASP397 | |
| A | THR521-ASP529 | |
| B | PHE285-ASN291 | |
| B | ASP397 | |
| B | THR521-ASP529 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20823549, ECO:0007744|PDB:3NH9 |
| Chain | Residue | Details |
| A | TYR599 | |
| A | GLY623 | |
| B | TYR599 | |
| B | GLY623 |
