8YMO
OSCA1.1-F516A pre-open 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005227 | molecular_function | calcium-activated cation channel activity |
| A | 0005261 | molecular_function | monoatomic cation channel activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006970 | biological_process | response to osmotic stress |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0051262 | biological_process | protein tetramerization |
| A | 0071474 | biological_process | cellular hyperosmotic response |
| A | 0090279 | biological_process | regulation of calcium ion import |
| A | 0098655 | biological_process | monoatomic cation transmembrane transport |
| C | 0005227 | molecular_function | calcium-activated cation channel activity |
| C | 0005261 | molecular_function | monoatomic cation channel activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006970 | biological_process | response to osmotic stress |
| C | 0034220 | biological_process | monoatomic ion transmembrane transport |
| C | 0051262 | biological_process | protein tetramerization |
| C | 0071474 | biological_process | cellular hyperosmotic response |
| C | 0090279 | biological_process | regulation of calcium ion import |
| C | 0098655 | biological_process | monoatomic cation transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 238 |
| Details | TOPO_DOM: Extracellular => ECO:0000305|PubMed:30190597 |
| Chain | Residue | Details |
| A | MET1-LYS5 | |
| C | ALA487-ALA527 | |
| C | MET590-LEU592 | |
| C | LEU647-ALA655 | |
| A | LEU120-ARG158 | |
| A | VAL397-SER424 | |
| A | ALA487-ALA527 | |
| A | MET590-LEU592 | |
| A | LEU647-ALA655 | |
| C | MET1-LYS5 | |
| C | LEU120-ARG158 | |
| C | VAL397-SER424 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 440 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | ASP6-ALA26 | |
| A | PRO626-LEU646 | |
| A | ALA656-ARG676 | |
| C | ASP6-ALA26 | |
| C | LEU99-VAL119 | |
| C | PHE159-LYS179 | |
| C | ARG376-PHE396 | |
| C | LEU425-ILE445 | |
| C | ALA466-ALA486 | |
| C | GLY528-PHE548 | |
| C | THR569-PRO589 | |
| A | LEU99-VAL119 | |
| C | PRO593-VAL613 | |
| C | PRO626-LEU646 | |
| C | ALA656-ARG676 | |
| A | PHE159-LYS179 | |
| A | ARG376-PHE396 | |
| A | LEU425-ILE445 | |
| A | ALA466-ALA486 | |
| A | GLY528-PHE548 | |
| A | THR569-PRO589 | |
| A | PRO593-VAL613 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 820 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:30190597 |
| Chain | Residue | Details |
| A | PHE27-TYR98 | |
| C | LEU549-ASN568 | |
| C | TYR614-TRP625 | |
| C | PHE677-VAL772 | |
| A | GLU180-ARG375 | |
| A | LEU446-SER465 | |
| A | LEU549-ASN568 | |
| A | TYR614-TRP625 | |
| A | PHE677-VAL772 | |
| C | PHE27-TYR98 | |
| C | GLU180-ARG375 | |
| C | LEU446-SER465 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc) asparagine => ECO:0000305|PubMed:30190597 |
| Chain | Residue | Details |
| A | ASN138 | |
| C | ASN138 |
