8YGY

Structure of the KLK1 from Biortus.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003073	biological_process	regulation of systemic arterial blood pressure
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005634	cellular_component	nucleus
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
A	0030141	cellular_component	secretory granule
A	0031638	biological_process	zymogen activation
A	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00134
Number of Residues	6
Details	TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC

Chain	Residue	Details
A	LEU61-CYS66

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site_id	PS00135
Number of Residues	12
Details	TRYPSIN_SER Serine proteases, trypsin family, serine active site. DTcvGDSGGPLM

Chain	Residue	Details
A	ASP208-MET219

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Charge relay system

Chain	Residue	Details
A	HIS65
A	ASP120
A	SER214

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site_id	SWS_FT_FI2
Number of Residues	3
Details	CARBOHYD: O-linked (GalNAc...) serine => ECO:0000269|PubMed:3163150

Chain	Residue	Details
A	SER93
A	SER104
A	SER167

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:3163150

Chain	Residue	Details
A	ASN102

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15651049, ECO:0000269|PubMed:3163150

Chain	Residue	Details
A	ASN108

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site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; partial => ECO:0000269|PubMed:3163150

Chain	Residue	Details
A	ASN165

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