8YGU

Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13-I54G mutant (right side)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019028	cellular_component	viral capsid
A	0019058	biological_process	viral life cycle
A	0019062	biological_process	virion attachment to host cell
A	0020002	cellular_component	host cell plasma membrane
A	0039624	cellular_component	viral outer capsid
A	0039665	biological_process	permeabilization of host organelle membrane involved in viral entry into host cell
A	0044163	cellular_component	host cytoskeleton
A	0044168	cellular_component	host cell rough endoplasmic reticulum
A	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
A	0044423	cellular_component	virion component
A	0046718	biological_process	symbiont entry into host cell
A	0140267	biological_process	symbiont entry into host cell via permeabilization of host membrane
B	0019028	cellular_component	viral capsid
B	0019058	biological_process	viral life cycle
C	0019028	cellular_component	viral capsid
C	0019058	biological_process	viral life cycle
C	0019062	biological_process	virion attachment to host cell
C	0020002	cellular_component	host cell plasma membrane
C	0039624	cellular_component	viral outer capsid
C	0039665	biological_process	permeabilization of host organelle membrane involved in viral entry into host cell
C	0044163	cellular_component	host cytoskeleton
C	0044168	cellular_component	host cell rough endoplasmic reticulum
C	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
C	0044423	cellular_component	virion component
C	0046718	biological_process	symbiont entry into host cell
C	0140267	biological_process	symbiont entry into host cell via permeabilization of host membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Region: {"description":"DGE motif; interaction with ITGA2/ITGB1 heterodimer","evidences":[{"source":"PubMed","id":"9144247","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	Region: {"description":"Hydrophobic; possible role in virus entry into host cell","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Motif: {"description":"DGE motif; interaction with ITGA2/ITGB1 heterodimer","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Motif: {"description":"YGL motif; interaction with ITGA4","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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