8YFU
Cryo EM structure of human phosphate channel XPR1 at intermediate state
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 328 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL237-PHE257 | |
| B | ILE265-LEU285 | |
| B | ILE319-ILE339 | |
| B | VAL346-TYR368 | |
| B | LEU377-ALA397 | |
| B | LEU403-TRP423 | |
| B | PHE474-TYR496 | |
| B | MET508-TRP528 | |
| A | ILE265-LEU285 | |
| A | ILE319-ILE339 | |
| A | VAL346-TYR368 | |
| A | LEU377-ALA397 | |
| A | LEU403-TRP423 | |
| A | PHE474-TYR496 | |
| A | MET508-TRP528 | |
| B | VAL237-PHE257 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 50 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS258-SER264 | |
| A | SER340-TYR345 | |
| A | ASP398-SER402 | |
| A | SER497-THR507 | |
| B | LYS258-SER264 | |
| B | SER340-TYR345 | |
| B | ASP398-SER402 | |
| B | SER497-THR507 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 176 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY286-GLU318 | |
| A | LYS369-LYS376 | |
| A | ASP424-ALA473 | |
| B | GLY286-GLU318 | |
| B | LYS369-LYS376 | |
| B | ASP424-ALA473 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Important for inositol polyphosphate binding => ECO:0000305|PubMed:27080106 |
| Chain | Residue | Details |
| A | TYR22 | |
| A | LYS26 | |
| B | TYR22 | |
| B | LYS26 |
