8YFS

MRGPRE-Gq-scFv16-complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0001750	cellular_component	photoreceptor outer segment
B	0001917	cellular_component	photoreceptor inner segment
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005834	cellular_component	heterotrimeric G-protein complex
B	0005886	cellular_component	plasma membrane
B	0007165	biological_process	signal transduction
B	0007186	biological_process	G protein-coupled receptor signaling pathway
B	0007200	biological_process	phospholipase C-activating G protein-coupled receptor signaling pathway
B	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
B	0008283	biological_process	cell population proliferation
B	0010659	biological_process	cardiac muscle cell apoptotic process
B	0030159	molecular_function	signaling receptor complex adaptor activity
B	0030425	cellular_component	dendrite
B	0030507	molecular_function	spectrin binding
B	0042622	cellular_component	photoreceptor outer segment membrane
B	0044297	cellular_component	cell body
B	0044877	molecular_function	protein-containing complex binding
B	0045202	cellular_component	synapse
B	0047391	molecular_function	alkylglycerophosphoethanolamine phosphodiesterase activity
B	0050909	biological_process	sensory perception of taste
B	0051020	molecular_function	GTPase binding
B	0060041	biological_process	retina development in camera-type eye
B	0071456	biological_process	cellular response to hypoxia
G	0003924	molecular_function	GTPase activity
G	0005515	molecular_function	protein binding
G	0005834	cellular_component	heterotrimeric G-protein complex
G	0005886	cellular_component	plasma membrane
G	0007165	biological_process	signal transduction
G	0007186	biological_process	G protein-coupled receptor signaling pathway
G	0007191	biological_process	adenylate cyclase-activating dopamine receptor signaling pathway
G	0016020	cellular_component	membrane
G	0031681	molecular_function	G-protein beta-subunit binding
G	0071380	biological_process	cellular response to prostaglandin E stimulus
G	0071870	biological_process	cellular response to catecholamine stimulus

Functional Information from PROSITE/UniProt

site_id	PS00237
Number of Residues	17
Details	G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. GGLsLLMAVSVERCLsV

Chain	Residue	Details
R	GLY134-VAL150

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site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS

Chain	Residue	Details
B	LEU70-SER84
B	ILE157-ILE171
B	LEU285-ALA299

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000305|PubMed:20966218, ECO:0007744|PDB:7SQ2

Chain	Residue	Details
A	SER44
A	ALA268
A	LYS270
A	SER331
A	GLY45
A	LYS46
A	THR48
A	SER60
A	LEU61
A	ARG61
A	ARG61
A	LEU267

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:20966218, ECO:0007744|PDB:7SQ2

Chain	Residue	Details
A	SER47
A	THR179

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: 5-glutamyl histamine => ECO:0000269|PubMed:23022564

Chain	Residue	Details
A	GLN202

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site_id	SWS_FT_FI4
Number of Residues	2
Details	LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:8227063

Chain	Residue	Details
A	CYS3
A	THR4

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