8YBB
Crystal structure of the sigma-1 receptor from Xenopus laevis with side opening
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | TOPO_DOM: Lumenal => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | MET1-TRP4 | |
| B | MET1-TRP4 | |
| C | MET1-TRP4 | |
| D | MET1-TRP4 | |
| E | MET1-TRP4 | |
| F | MET1-TRP4 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 132 |
| Details | TRANSMEM: Helical => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | LEU5-LEU27 | |
| B | LEU5-LEU27 | |
| C | LEU5-LEU27 | |
| D | LEU5-LEU27 | |
| E | LEU5-LEU27 | |
| F | LEU5-LEU27 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1158 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | SER28-PHE221 | |
| B | SER28-PHE221 | |
| C | SER28-PHE221 | |
| D | SER28-PHE221 | |
| E | SER28-PHE221 | |
| F | SER28-PHE221 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | SITE: Important for ligand binding => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | ASP123 | |
| E | GLU169 | |
| F | ASP123 | |
| F | GLU169 | |
| A | GLU169 | |
| B | ASP123 | |
| B | GLU169 | |
| C | ASP123 | |
| C | GLU169 | |
| D | ASP123 | |
| D | GLU169 | |
| E | ASP123 |
