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8YAR

ATAT-2 bound K40R MEC-12/MEC-7 microtubule

Functional Information from GO Data
ChainGOidnamespacecontents
B0000166molecular_functionnucleotide binding
B0000226biological_processmicrotubule cytoskeleton organization
B0000278biological_processmitotic cell cycle
B0001966biological_processthigmotaxis
B0005200molecular_functionstructural constituent of cytoskeleton
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005874cellular_componentmicrotubule
B0007017biological_processmicrotubule-based process
B0007638biological_processmechanosensory behavior
B0009612biological_processresponse to mechanical stimulus
B0016787molecular_functionhydrolase activity
B0030424cellular_componentaxon
B0043025cellular_componentneuronal cell body
B0046872molecular_functionmetal ion binding
B0050976biological_processdetection of mechanical stimulus involved in sensory perception of touch
B1905789biological_processpositive regulation of detection of mechanical stimulus involved in sensory perception of touch
B1905792biological_processpositive regulation of mechanosensory behavior
C0000226biological_processmicrotubule cytoskeleton organization
C0001966biological_processthigmotaxis
C0004468molecular_functionL-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
C0005874cellular_componentmicrotubule
C0016740molecular_functiontransferase activity
C0016746molecular_functionacyltransferase activity
C0019799molecular_functiontubulin N-acetyltransferase activity
C0048666biological_processneuron development
C0070507biological_processregulation of microtubule cytoskeleton organization
C0071929biological_processalpha-tubulin acetylation
D0000166molecular_functionnucleotide binding
D0000226biological_processmicrotubule cytoskeleton organization
D0000278biological_processmitotic cell cycle
D0003924molecular_functionGTPase activity
D0005200molecular_functionstructural constituent of cytoskeleton
D0005525molecular_functionGTP binding
D0005737cellular_componentcytoplasm
D0005856cellular_componentcytoskeleton
D0005874cellular_componentmicrotubule
D0007017biological_processmicrotubule-based process
D0007638biological_processmechanosensory behavior
D0009612biological_processresponse to mechanical stimulus
D0031122biological_processcytoplasmic microtubule organization
D0043005cellular_componentneuron projection
D0043025cellular_componentneuronal cell body
D0046872molecular_functionmetal ion binding
D0050974biological_processdetection of mechanical stimulus involved in sensory perception
D0050976biological_processdetection of mechanical stimulus involved in sensory perception of touch
D1905789biological_processpositive regulation of detection of mechanical stimulus involved in sensory perception of touch
D1905792biological_processpositive regulation of mechanosensory behavior
E0000166molecular_functionnucleotide binding
E0000226biological_processmicrotubule cytoskeleton organization
E0000278biological_processmitotic cell cycle
E0001966biological_processthigmotaxis
E0005200molecular_functionstructural constituent of cytoskeleton
E0005525molecular_functionGTP binding
E0005737cellular_componentcytoplasm
E0005874cellular_componentmicrotubule
E0007017biological_processmicrotubule-based process
E0007638biological_processmechanosensory behavior
E0009612biological_processresponse to mechanical stimulus
E0016787molecular_functionhydrolase activity
E0030424cellular_componentaxon
E0043025cellular_componentneuronal cell body
E0046872molecular_functionmetal ion binding
E0050976biological_processdetection of mechanical stimulus involved in sensory perception of touch
E1905789biological_processpositive regulation of detection of mechanical stimulus involved in sensory perception of touch
E1905792biological_processpositive regulation of mechanosensory behavior
F0000166molecular_functionnucleotide binding
F0000226biological_processmicrotubule cytoskeleton organization
F0000278biological_processmitotic cell cycle
F0003924molecular_functionGTPase activity
F0005200molecular_functionstructural constituent of cytoskeleton
F0005525molecular_functionGTP binding
F0005737cellular_componentcytoplasm
F0005856cellular_componentcytoskeleton
F0005874cellular_componentmicrotubule
F0007017biological_processmicrotubule-based process
F0007638biological_processmechanosensory behavior
F0009612biological_processresponse to mechanical stimulus
F0031122biological_processcytoplasmic microtubule organization
F0043005cellular_componentneuron projection
F0043025cellular_componentneuronal cell body
F0046872molecular_functionmetal ion binding
F0050974biological_processdetection of mechanical stimulus involved in sensory perception
F0050976biological_processdetection of mechanical stimulus involved in sensory perception of touch
F1905789biological_processpositive regulation of detection of mechanical stimulus involved in sensory perception of touch
F1905792biological_processpositive regulation of mechanosensory behavior
I0000226biological_processmicrotubule cytoskeleton organization
I0001966biological_processthigmotaxis
I0004468molecular_functionL-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
I0005874cellular_componentmicrotubule
I0016740molecular_functiontransferase activity
I0016746molecular_functionacyltransferase activity
I0019799molecular_functiontubulin N-acetyltransferase activity
I0048666biological_processneuron development
I0070507biological_processregulation of microtubule cytoskeleton organization
I0071929biological_processalpha-tubulin acetylation
Functional Information from PROSITE/UniProt
site_idPS00227
Number of Residues7
DetailsTUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG
ChainResidueDetails
BGLY142-GLY148
DGLY140-GLY146

site_idPS00228
Number of Residues4
DetailsTUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI
ChainResidueDetails
DMET1-ILE4

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q13509
ChainResidueDetails
DGLN11
FGLY142
FTHR143
FGLY144
FASN204
FASN226
DSER138
DGLY142
DTHR143
DGLY144
DASN204
DASN226
FGLN11
FSER138

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P68363
ChainResidueDetails
DGLU69
EGLU71
ESER140
EGLY144
ETHR145
ETHR179
EASN206
EASN228
FGLU69
BSER140
BGLY144
BTHR145
BTHR179
BASN206
BASN228
EGLN11

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Involved in polymerization
ChainResidueDetails
BTYR450
ETYR450

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000269|PubMed:20829795, ECO:0000269|PubMed:9885292
ChainResidueDetails
BARG40
EARG40

236620

PDB entries from 2025-05-28

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