Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8YAL

ATAT-2 bound K40Q MEC-12/MEC-7 microtubule

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000166	molecular_function	nucleotide binding
B	0000226	biological_process	microtubule cytoskeleton organization
B	0000278	biological_process	mitotic cell cycle
B	0001966	biological_process	thigmotaxis
B	0005200	molecular_function	structural constituent of cytoskeleton
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005874	cellular_component	microtubule
B	0007017	biological_process	microtubule-based process
B	0007638	biological_process	mechanosensory behavior
B	0009612	biological_process	response to mechanical stimulus
B	0016787	molecular_function	hydrolase activity
B	0030424	cellular_component	axon
B	0043025	cellular_component	neuronal cell body
B	0046872	molecular_function	metal ion binding
B	0050976	biological_process	detection of mechanical stimulus involved in sensory perception of touch
B	1905789	biological_process	positive regulation of detection of mechanical stimulus involved in sensory perception of touch
B	1905792	biological_process	positive regulation of mechanosensory behavior
C	0000226	biological_process	microtubule cytoskeleton organization
C	0001966	biological_process	thigmotaxis
C	0004468	molecular_function	L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
C	0005874	cellular_component	microtubule
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0019799	molecular_function	tubulin N-acetyltransferase activity
C	0048666	biological_process	neuron development
C	0070507	biological_process	regulation of microtubule cytoskeleton organization
C	0071929	biological_process	alpha-tubulin acetylation
D	0000166	molecular_function	nucleotide binding
D	0000226	biological_process	microtubule cytoskeleton organization
D	0000278	biological_process	mitotic cell cycle
D	0003924	molecular_function	GTPase activity
D	0005200	molecular_function	structural constituent of cytoskeleton
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005856	cellular_component	cytoskeleton
D	0005874	cellular_component	microtubule
D	0007017	biological_process	microtubule-based process
D	0007638	biological_process	mechanosensory behavior
D	0009612	biological_process	response to mechanical stimulus
D	0031122	biological_process	cytoplasmic microtubule organization
D	0043005	cellular_component	neuron projection
D	0043025	cellular_component	neuronal cell body
D	0046872	molecular_function	metal ion binding
D	0050974	biological_process	detection of mechanical stimulus involved in sensory perception
D	0050976	biological_process	detection of mechanical stimulus involved in sensory perception of touch
D	1905789	biological_process	positive regulation of detection of mechanical stimulus involved in sensory perception of touch
D	1905792	biological_process	positive regulation of mechanosensory behavior
E	0000166	molecular_function	nucleotide binding
E	0000226	biological_process	microtubule cytoskeleton organization
E	0000278	biological_process	mitotic cell cycle
E	0001966	biological_process	thigmotaxis
E	0005200	molecular_function	structural constituent of cytoskeleton
E	0005525	molecular_function	GTP binding
E	0005737	cellular_component	cytoplasm
E	0005874	cellular_component	microtubule
E	0007017	biological_process	microtubule-based process
E	0007638	biological_process	mechanosensory behavior
E	0009612	biological_process	response to mechanical stimulus
E	0016787	molecular_function	hydrolase activity
E	0030424	cellular_component	axon
E	0043025	cellular_component	neuronal cell body
E	0046872	molecular_function	metal ion binding
E	0050976	biological_process	detection of mechanical stimulus involved in sensory perception of touch
E	1905789	biological_process	positive regulation of detection of mechanical stimulus involved in sensory perception of touch
E	1905792	biological_process	positive regulation of mechanosensory behavior
F	0000166	molecular_function	nucleotide binding
F	0000226	biological_process	microtubule cytoskeleton organization
F	0000278	biological_process	mitotic cell cycle
F	0003924	molecular_function	GTPase activity
F	0005200	molecular_function	structural constituent of cytoskeleton
F	0005525	molecular_function	GTP binding
F	0005737	cellular_component	cytoplasm
F	0005856	cellular_component	cytoskeleton
F	0005874	cellular_component	microtubule
F	0007017	biological_process	microtubule-based process
F	0007638	biological_process	mechanosensory behavior
F	0009612	biological_process	response to mechanical stimulus
F	0031122	biological_process	cytoplasmic microtubule organization
F	0043005	cellular_component	neuron projection
F	0043025	cellular_component	neuronal cell body
F	0046872	molecular_function	metal ion binding
F	0050974	biological_process	detection of mechanical stimulus involved in sensory perception
F	0050976	biological_process	detection of mechanical stimulus involved in sensory perception of touch
F	1905789	biological_process	positive regulation of detection of mechanical stimulus involved in sensory perception of touch
F	1905792	biological_process	positive regulation of mechanosensory behavior
I	0000226	biological_process	microtubule cytoskeleton organization
I	0001966	biological_process	thigmotaxis
I	0004468	molecular_function	L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
I	0005874	cellular_component	microtubule
I	0016740	molecular_function	transferase activity
I	0016746	molecular_function	acyltransferase activity
I	0019799	molecular_function	tubulin N-acetyltransferase activity
I	0048666	biological_process	neuron development
I	0070507	biological_process	regulation of microtubule cytoskeleton organization
I	0071929	biological_process	alpha-tubulin acetylation

Functional Information from PROSITE/UniProt

site_id	PS00227
Number of Residues	7
Details	TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG

Chain	Residue	Details
D	GLY140-GLY146
B	GLY142-GLY148

site_id	PS00228
Number of Residues	4
Details	TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI

Chain	Residue	Details
D	MET1-ILE4

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"20829795","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9885292","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	180
Details	Domain: {"description":"N-acetyltransferase","evidences":[{"source":"HAMAP-Rule","id":"MF_03130","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03130","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	21
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	10
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q13509","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)