8YAD

structure of SPG11-SPG15 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005764	cellular_component	lysosome
B	0005765	cellular_component	lysosomal membrane
B	0005770	cellular_component	late endosome
B	0005783	cellular_component	endoplasmic reticulum
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0007040	biological_process	lysosome organization
B	0007268	biological_process	chemical synaptic transmission
B	0007409	biological_process	axonogenesis
B	0008088	biological_process	axo-dendritic transport
B	0019901	molecular_function	protein kinase binding
B	0030424	cellular_component	axon
B	0030425	cellular_component	dendrite
B	0031410	cellular_component	cytoplasmic vesicle
B	0045202	cellular_component	synapse
B	0048489	biological_process	synaptic vesicle transport
B	0097212	biological_process	lysosomal membrane organization
B	0097753	biological_process	membrane bending
B	1905037	biological_process	autophagosome organization
C	0000281	biological_process	mitotic cytokinesis
C	0000724	biological_process	double-strand break repair via homologous recombination
C	0005515	molecular_function	protein binding
C	0005764	cellular_component	lysosome
C	0005765	cellular_component	lysosomal membrane
C	0005769	cellular_component	early endosome
C	0005770	cellular_component	late endosome
C	0005813	cellular_component	centrosome
C	0006281	biological_process	DNA repair
C	0006974	biological_process	DNA damage response
C	0007040	biological_process	lysosome organization
C	0008270	molecular_function	zinc ion binding
C	0008289	molecular_function	lipid binding
C	0019901	molecular_function	protein kinase binding
C	0030496	cellular_component	midbody
C	0032266	molecular_function	phosphatidylinositol-3-phosphate binding
C	0032465	biological_process	regulation of cytokinesis
C	0046872	molecular_function	metal ion binding
C	0051301	biological_process	cell division
C	0097212	biological_process	lysosomal membrane organization
C	0097753	biological_process	membrane bending
C	1905037	biological_process	autophagosome organization

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	25
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CeewgClypIprehlislHqkhllH

Chain	Residue	Details
C	CYS1563-HIS1587

---

site_id	PS00572
Number of Residues	9
Details	GLYCOSYL_HYDROL_F1_1 Glycosyl hydrolases family 1 active site. FVLTENGLS

Chain	Residue	Details
B	PHE482-SER490

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00091","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---