8Y9C
De novo design mini-binder in complex with TcdB4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0008289 | molecular_function | lipid binding |
| B | 0016020 | cellular_component | membrane |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0020002 | cellular_component | host cell plasma membrane |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0033644 | cellular_component | host cell membrane |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0044164 | cellular_component | host cell cytosol |
| B | 0044174 | cellular_component | host cell endosome |
| B | 0044175 | cellular_component | host cell endosome membrane |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0090729 | molecular_function | toxin activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: For protease activity => ECO:0000255|PROSITE-ProRule:PRU01107 |
| Chain | Residue | Details |
| B | HIS654 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile; for protease activity => ECO:0000255|PROSITE-ProRule:PRU01107 |
| Chain | Residue | Details |
| B | CYS699 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 11 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P18177 |
| Chain | Residue | Details |
| B | ILE101 | |
| B | HIS654 | |
| B | HIS758 | |
| B | ASN139 | |
| B | SER269 | |
| B | ASP286 | |
| B | ASP288 | |
| B | GLU516 | |
| B | SER519 | |
| B | GLU546 | |
| B | ASP547 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P16154 |
| Chain | Residue | Details |
| B | TYR578 | |
| B | LYS601 | |
| B | LYS648 | |
| B | LYS765 | |
| B | LYS776 | |
| B | LYS793 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:15632438 |
| Chain | Residue | Details |
| B | LEU544 |
