8Y9B
TcdB1 in complex with mini-binder
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: For protease activity => ECO:0000255|PROSITE-ProRule:PRU01107, ECO:0000269|PubMed:27571750 |
| Chain | Residue | Details |
| B | HIS653 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile; for protease activity => ECO:0000255|PROSITE-ProRule:PRU01107, ECO:0000269|PubMed:27571750 |
| Chain | Residue | Details |
| B | CYS698 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16054646, ECO:0000269|PubMed:28433497, ECO:0000269|PubMed:31308519, ECO:0007744|PDB:2BVL, ECO:0007744|PDB:2BVM, ECO:0007744|PDB:5UQM, ECO:0007744|PDB:5UQN, ECO:0007744|PDB:6OQ7 |
| Chain | Residue | Details |
| B | VAL101 | |
| B | SER269 | |
| B | SER518 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16054646, ECO:0000269|PubMed:28433497, ECO:0007744|PDB:2BVL, ECO:0007744|PDB:2BVM, ECO:0007744|PDB:5UQM, ECO:0007744|PDB:5UQN |
| Chain | Residue | Details |
| B | ASN139 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:31308519, ECO:0007744|PDB:6OQ5 |
| Chain | Residue | Details |
| B | ASP286 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16054646, ECO:0000269|PubMed:28433497, ECO:0000305|PubMed:31308519, ECO:0007744|PDB:2BVL, ECO:0007744|PDB:5UQM, ECO:0007744|PDB:5UQN, ECO:0007744|PDB:5UQT, ECO:0007744|PDB:6OQ7 |
| Chain | Residue | Details |
| B | ASP288 | |
| B | GLU515 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P16154 |
| Chain | Residue | Details |
| B | GLU545 | |
| B | TYR577 | |
| B | LYS600 | |
| B | LYS647 | |
| B | LYS764 | |
| B | LYS775 | |
| B | LYS792 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31308519, ECO:0007744|PDB:6OQ5 |
| Chain | Residue | Details |
| B | ASP546 | |
| B | HIS653 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31308519, ECO:0000305|PubMed:27571750, ECO:0007744|PDB:6OQ5 |
| Chain | Residue | Details |
| B | HIS757 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:15632438 |
| Chain | Residue | Details |
| B | LEU543 |
