8Y8X
Cryo-EM structure of GlpF with P177 deletion in POPC nanodisc
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005372 | molecular_function | water transmembrane transporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006833 | biological_process | water transport |
| A | 0015168 | molecular_function | glycerol transmembrane transporter activity |
| A | 0015254 | molecular_function | glycerol channel activity |
| A | 0015793 | biological_process | glycerol transmembrane transport |
| A | 0016020 | cellular_component | membrane |
| A | 0071288 | biological_process | cellular response to mercury ion |
Functional Information from PROSITE/UniProt
| site_id | PS00221 |
| Number of Residues | 9 |
| Details | MIP MIP family signature. HLNPAVTIA |
| Chain | Residue | Details |
| A | HIS66-ALA74 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Transmembrane: {"description":"Helical; Name=M1","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 55 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=M2","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Intramembrane: {"evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 10 |
| Details | Intramembrane: {"description":"Helical; Name=M3","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=M4","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=M5","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 16 |
| Details | Transmembrane: {"description":"Helical; Name=M6","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 13 |
| Details | Intramembrane: {"description":"Helical; Name=M7","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=M8","evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | Motif: {"description":"NPA 1","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | Motif: {"description":"NPA 2","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11964478","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FX8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11964478","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FX8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11039922","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FX8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 3 |
| Details | Site: {"description":"Substrate discrimination","evidences":[{"source":"PubMed","id":"11101882","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
