8Y86

Human AE3 with NaHCO3-

Functional Information from PROSITE/UniProt

site_id	PS00219
Number of Residues	12
Details	ANION_EXCHANGER_1 Anion exchangers family signature 1. FGGLVRDVRRRY

Chain	Residue	Details
A	PHE682-TYR693

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site_id	PS00220
Number of Residues	15
Details	ANION_EXCHANGER_2 Anion exchangers family signature 2. FLISLIFIYETFyKL

Chain	Residue	Details
A	PHE829-LEU843

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1414
Details	TOPO_DOM: Cytoplasmic

Chain	Residue	Details
A	MET1-CYS708
B	MET1-CYS708

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site_id	SWS_FT_FI2
Number of Residues	526
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	VAL709-GLY731
A	MET1155-LEU1191
B	VAL709-GLY731
B	LEU737-PHE774
B	VAL794-VAL816
B	ILE826-PHE847
B	ALA893-LEU910
B	ILE926-ILE946
B	PRO980-MET1002
B	LEU1028-ALA1049
B	VAL1083-SER1128
A	LEU737-PHE774
B	MET1155-LEU1191
A	VAL794-VAL816
A	ILE826-PHE847
A	ALA893-LEU910
A	ILE926-ILE946
A	PRO980-MET1002
A	LEU1028-ALA1049
A	VAL1083-SER1128

---

site_id	SWS_FT_FI3
Number of Residues	28
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	ARG911-ARG925
B	ARG911-ARG925

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site_id	SWS_FT_FI4
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P16283

Chain	Residue	Details
A	SER167
A	SER170
A	SER198
B	SER167
B	SER170
B	SER198

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site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P23348

Chain	Residue	Details
A	SER175
B	SER175

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site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:P16283

Chain	Residue	Details
A	ARG295
B	ARG295

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site_id	SWS_FT_FI7
Number of Residues	2
Details	LIPID: S-palmitoyl cysteine => ECO:0000250

Chain	Residue	Details
A	CYS1165
B	CYS1165

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