8Y86

Human AE3 with NaHCO3-

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005452	molecular_function	solute:inorganic anion antiporter activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006820	biological_process	monoatomic anion transport
A	0008509	molecular_function	monoatomic anion transmembrane transporter activity
A	0009897	cellular_component	external side of plasma membrane
A	0015106	molecular_function	bicarbonate transmembrane transporter activity
A	0015297	molecular_function	antiporter activity
A	0015701	biological_process	bicarbonate transport
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0045851	biological_process	pH reduction
A	0051453	biological_process	regulation of intracellular pH
A	0055085	biological_process	transmembrane transport
A	0061337	biological_process	cardiac conduction
A	0086001	biological_process	cardiac muscle cell action potential
A	0098656	biological_process	monoatomic anion transmembrane transport
A	0098901	biological_process	regulation of cardiac muscle cell action potential
A	0140900	molecular_function	chloride:bicarbonate antiporter activity
A	0150104	biological_process	transport across blood-brain barrier
A	1902476	biological_process	chloride transmembrane transport
B	0005452	molecular_function	solute:inorganic anion antiporter activity
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0006820	biological_process	monoatomic anion transport
B	0008509	molecular_function	monoatomic anion transmembrane transporter activity
B	0009897	cellular_component	external side of plasma membrane
B	0015106	molecular_function	bicarbonate transmembrane transporter activity
B	0015297	molecular_function	antiporter activity
B	0015701	biological_process	bicarbonate transport
B	0016020	cellular_component	membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0045851	biological_process	pH reduction
B	0051453	biological_process	regulation of intracellular pH
B	0055085	biological_process	transmembrane transport
B	0061337	biological_process	cardiac conduction
B	0086001	biological_process	cardiac muscle cell action potential
B	0098656	biological_process	monoatomic anion transmembrane transport
B	0098901	biological_process	regulation of cardiac muscle cell action potential
B	0140900	molecular_function	chloride:bicarbonate antiporter activity
B	0150104	biological_process	transport across blood-brain barrier
B	1902476	biological_process	chloride transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00219
Number of Residues	12
Details	ANION_EXCHANGER_1 Anion exchangers family signature 1. FGGLVRDVRRRY

Chain	Residue	Details
A	PHE682-TYR693

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site_id	PS00220
Number of Residues	15
Details	ANION_EXCHANGER_2 Anion exchangers family signature 2. FLISLIFIYETFyKL

Chain	Residue	Details
A	PHE829-LEU843

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	526
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	28
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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