8Y5J
Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | ILE692 | |
| B | ILE692 | |
| C | ILE692 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | PHE822 | |
| B | PHE822 | |
| C | PHE822 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN20 | |
| A | LEU1165 | |
| A | LYS1180 | |
| B | ASN20 | |
| B | LEU1165 | |
| B | LYS1180 | |
| C | ASN20 | |
| C | LEU1165 | |
| C | LYS1180 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | TRP64 | |
| B | CYS1081 | |
| C | TRP64 | |
| C | PHE127 | |
| C | GLU724 | |
| C | PRO808 | |
| C | CYS1081 | |
| A | PHE127 | |
| A | GLU724 | |
| A | PRO808 | |
| A | CYS1081 | |
| B | TRP64 | |
| B | PHE127 | |
| B | GLU724 | |
| B | PRO808 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | PHE79 | |
| A | SER155 | |
| A | GLU1201 | |
| B | PHE79 | |
| B | SER155 | |
| B | GLU1201 | |
| C | PHE79 | |
| C | SER155 | |
| C | GLU1201 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 21 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | VAL171 | |
| B | PHE338 | |
| B | VAL350 | |
| B | ILE623 | |
| B | PRO664 | |
| B | GLN1105 | |
| C | VAL171 | |
| C | VAL289 | |
| C | PHE338 | |
| C | VAL350 | |
| C | ILE623 | |
| A | VAL289 | |
| C | PRO664 | |
| C | GLN1105 | |
| A | PHE338 | |
| A | VAL350 | |
| A | ILE623 | |
| A | PRO664 | |
| A | GLN1105 | |
| B | VAL171 | |
| B | VAL289 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | LEU241 | |
| A | ASN716 | |
| B | LEU241 | |
| B | ASN716 | |
| C | LEU241 | |
| C | ASN716 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | PRO330 | |
| B | PRO330 | |
| C | PRO330 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | VAL332 | |
| B | VAL332 | |
| C | VAL332 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | LEU610 | |
| B | LEU610 | |
| C | LEU610 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
| Chain | Residue | Details |
| A | ALA683 | |
| A | SER685 | |
| B | ALA683 | |
| B | SER685 | |
| C | ALA683 | |
| C | SER685 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | GLN1141 | |
| B | GLN1141 | |
| C | GLN1141 |
