Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8Y36

cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190.

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0005737	cellular_component	cytoplasm
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
1	1990904	cellular_component	ribonucleoprotein complex
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
2	1990904	cellular_component	ribonucleoprotein complex
3	0003735	molecular_function	structural constituent of ribosome
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	0022625	cellular_component	cytosolic large ribosomal subunit
3	1990904	cellular_component	ribonucleoprotein complex
4	0005737	cellular_component	cytoplasm
4	0005840	cellular_component	ribosome
4	0006412	biological_process	translation
4	1990904	cellular_component	ribonucleoprotein complex
C	0002181	biological_process	cytoplasmic translation
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0019843	molecular_function	rRNA binding
C	1990904	cellular_component	ribonucleoprotein complex
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0019843	molecular_function	rRNA binding
D	0022625	cellular_component	cytosolic large ribosomal subunit
D	1990904	cellular_component	ribonucleoprotein complex
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
E	1990904	cellular_component	ribonucleoprotein complex
F	0000049	molecular_function	tRNA binding
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
F	1990904	cellular_component	ribonucleoprotein complex
G	0002181	biological_process	cytoplasmic translation
G	0003735	molecular_function	structural constituent of ribosome
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0019843	molecular_function	rRNA binding
G	0022625	cellular_component	cytosolic large ribosomal subunit
G	1990904	cellular_component	ribonucleoprotein complex
H	0003729	molecular_function	mRNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005737	cellular_component	cytoplasm
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0017148	biological_process	negative regulation of translation
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	1990904	cellular_component	ribonucleoprotein complex
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0019843	molecular_function	rRNA binding
I	0022625	cellular_component	cytosolic large ribosomal subunit
I	0070180	molecular_function	large ribosomal subunit rRNA binding
I	1990904	cellular_component	ribonucleoprotein complex
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0019843	molecular_function	rRNA binding
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	1990904	cellular_component	ribonucleoprotein complex
K	0000049	molecular_function	tRNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0019843	molecular_function	rRNA binding
K	0022625	cellular_component	cytosolic large ribosomal subunit
K	1990904	cellular_component	ribonucleoprotein complex
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
M	0005737	cellular_component	cytoplasm
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0008097	molecular_function	5S rRNA binding
M	0019843	molecular_function	rRNA binding
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	1990904	cellular_component	ribonucleoprotein complex
O	0000027	biological_process	ribosomal large subunit assembly
O	0005840	cellular_component	ribosome
O	0019843	molecular_function	rRNA binding
O	1990904	cellular_component	ribonucleoprotein complex
P	0003735	molecular_function	structural constituent of ribosome
P	0005737	cellular_component	cytoplasm
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0019843	molecular_function	rRNA binding
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0019843	molecular_function	rRNA binding
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	1990904	cellular_component	ribonucleoprotein complex
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0019843	molecular_function	rRNA binding
R	1990904	cellular_component	ribonucleoprotein complex
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0019843	molecular_function	rRNA binding
S	1990904	cellular_component	ribonucleoprotein complex
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	1990904	cellular_component	ribonucleoprotein complex
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0022625	cellular_component	cytosolic large ribosomal subunit
W	1990904	cellular_component	ribonucleoprotein complex
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0022625	cellular_component	cytosolic large ribosomal subunit
X	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00014
Number of Residues	4
Details	ER_TARGET Endoplasmic reticulum targeting sequence. REEL

Chain	Residue	Details
K	ARG134-LEU137

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVIVrtksgvrrn.DGsyikFdeNacVI

Chain	Residue	Details
I	ALA60-ILE86

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LelITGQkpLvTkAKkS

Chain	Residue	Details
F	LEU57-SER73

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KrfRpRAqGRasainkrtSHITIvV

Chain	Residue	Details
Q	LYS83-VAL107

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGSVmNPnD

Chain	Residue	Details
C	PRO218-ASP229

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FvagdviDvtGvSkGKGfqGaikR

Chain	Residue	Details
D	PHE110-ARG133

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KILGnGsLdkk..LtVkahkFSasAaeaIdakG

Chain	Residue	Details
J	LYS110-GLY140

site_id	PS00525
Number of Residues	9
Details	RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGI

Chain	Residue	Details
G	PRO154-ILE162

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YiTtKNkrnnPerIEmkKYC

Chain	Residue	Details
1	TYR17-CYS36

site_id	PS00586
Number of Residues	12
Details	RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRgGKVWIKIFP

Chain	Residue	Details
K	LYS59-PRO70

site_id	PS00701
Number of Residues	12
Details	RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGaGKGavegW

Chain	Residue	Details
K	ARG82-TRP93

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. IKGMLPstrl.GEkqgkkLfVYgG

Chain	Residue	Details
H	ILE106-GLY128

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTYQpnkrkHskvh.GFrkR

Chain	Residue	Details
2	LYS3-ARG22

site_id	PS00828
Number of Residues	26
Details	RIBOSOMAL_L36 Ribosomal protein L36 signature. CekCkvIkRkgkVmViCenp.KHkQrQ

Chain	Residue	Details
4	CYS11-GLN36

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GsILyRQRGtkiypG

Chain	Residue	Details
U	GLY42-GLY56

site_id	PS00936
Number of Residues	27
Details	RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHrGAaKRVkrtasgqlkrsraft.SH

Chain	Residue	Details
3	LYS5-HIS31

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KrdfRkLWITRINaaaR

Chain	Residue	Details
O	LYS54-ARG70

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGKVR.RAKLYYLR

Chain	Residue	Details
N	VAL88-ARG103

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDnVkVIaGkdKGke.GkV

Chain	Residue	Details
S	GLY6-VAL23

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IeTTeaRaKevrsvvEkLITlGK

Chain	Residue	Details
L	ILE30-LYS52

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)