8Y2H

GK tetramer of AtP5CS1 filament with adjacent hooks, reaction state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0004349	molecular_function	glutamate 5-kinase activity
A	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0006561	biological_process	proline biosynthetic process
A	0006979	biological_process	response to oxidative stress
A	0008652	biological_process	amino acid biosynthetic process
A	0009414	biological_process	response to water deprivation
A	0009507	cellular_component	chloroplast
A	0009555	biological_process	pollen development
A	0009651	biological_process	response to salt stress
A	0010228	biological_process	vegetative to reproductive phase transition of meristem
A	0016301	molecular_function	kinase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0016740	molecular_function	transferase activity
A	0017084	molecular_function	delta1-pyrroline-5-carboxylate synthetase activity
A	0042538	biological_process	hyperosmotic salinity response
A	0048364	biological_process	root development
A	0055129	biological_process	L-proline biosynthetic process
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0004349	molecular_function	glutamate 5-kinase activity
B	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005794	cellular_component	Golgi apparatus
B	0006561	biological_process	proline biosynthetic process
B	0006979	biological_process	response to oxidative stress
B	0008652	biological_process	amino acid biosynthetic process
B	0009414	biological_process	response to water deprivation
B	0009507	cellular_component	chloroplast
B	0009555	biological_process	pollen development
B	0009651	biological_process	response to salt stress
B	0010228	biological_process	vegetative to reproductive phase transition of meristem
B	0016301	molecular_function	kinase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0016740	molecular_function	transferase activity
B	0017084	molecular_function	delta1-pyrroline-5-carboxylate synthetase activity
B	0042538	biological_process	hyperosmotic salinity response
B	0048364	biological_process	root development
B	0055129	biological_process	L-proline biosynthetic process
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0004349	molecular_function	glutamate 5-kinase activity
C	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005794	cellular_component	Golgi apparatus
C	0006561	biological_process	proline biosynthetic process
C	0006979	biological_process	response to oxidative stress
C	0008652	biological_process	amino acid biosynthetic process
C	0009414	biological_process	response to water deprivation
C	0009507	cellular_component	chloroplast
C	0009555	biological_process	pollen development
C	0009651	biological_process	response to salt stress
C	0010228	biological_process	vegetative to reproductive phase transition of meristem
C	0016301	molecular_function	kinase activity
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0016740	molecular_function	transferase activity
C	0017084	molecular_function	delta1-pyrroline-5-carboxylate synthetase activity
C	0042538	biological_process	hyperosmotic salinity response
C	0048364	biological_process	root development
C	0055129	biological_process	L-proline biosynthetic process
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0004349	molecular_function	glutamate 5-kinase activity
D	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005794	cellular_component	Golgi apparatus
D	0006561	biological_process	proline biosynthetic process
D	0006979	biological_process	response to oxidative stress
D	0008652	biological_process	amino acid biosynthetic process
D	0009414	biological_process	response to water deprivation
D	0009507	cellular_component	chloroplast
D	0009555	biological_process	pollen development
D	0009651	biological_process	response to salt stress
D	0010228	biological_process	vegetative to reproductive phase transition of meristem
D	0016301	molecular_function	kinase activity
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0016740	molecular_function	transferase activity
D	0017084	molecular_function	delta1-pyrroline-5-carboxylate synthetase activity
D	0042538	biological_process	hyperosmotic salinity response
D	0048364	biological_process	root development
D	0055129	biological_process	L-proline biosynthetic process
E	0000166	molecular_function	nucleotide binding
E	0003824	molecular_function	catalytic activity
E	0004349	molecular_function	glutamate 5-kinase activity
E	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005794	cellular_component	Golgi apparatus
E	0006561	biological_process	proline biosynthetic process
E	0006979	biological_process	response to oxidative stress
E	0008652	biological_process	amino acid biosynthetic process
E	0009414	biological_process	response to water deprivation
E	0009507	cellular_component	chloroplast
E	0009555	biological_process	pollen development
E	0009651	biological_process	response to salt stress
E	0010228	biological_process	vegetative to reproductive phase transition of meristem
E	0016301	molecular_function	kinase activity
E	0016491	molecular_function	oxidoreductase activity
E	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
E	0016740	molecular_function	transferase activity
E	0017084	molecular_function	delta1-pyrroline-5-carboxylate synthetase activity
E	0042538	biological_process	hyperosmotic salinity response
E	0048364	biological_process	root development
E	0055129	biological_process	L-proline biosynthetic process
F	0000166	molecular_function	nucleotide binding
F	0003824	molecular_function	catalytic activity
F	0004349	molecular_function	glutamate 5-kinase activity
F	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005794	cellular_component	Golgi apparatus
F	0006561	biological_process	proline biosynthetic process
F	0006979	biological_process	response to oxidative stress
F	0008652	biological_process	amino acid biosynthetic process
F	0009414	biological_process	response to water deprivation
F	0009507	cellular_component	chloroplast
F	0009555	biological_process	pollen development
F	0009651	biological_process	response to salt stress
F	0010228	biological_process	vegetative to reproductive phase transition of meristem
F	0016301	molecular_function	kinase activity
F	0016491	molecular_function	oxidoreductase activity
F	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
F	0016740	molecular_function	transferase activity
F	0017084	molecular_function	delta1-pyrroline-5-carboxylate synthetase activity
F	0042538	biological_process	hyperosmotic salinity response
F	0048364	biological_process	root development
F	0055129	biological_process	L-proline biosynthetic process
G	0000166	molecular_function	nucleotide binding
G	0003824	molecular_function	catalytic activity
G	0004349	molecular_function	glutamate 5-kinase activity
G	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005794	cellular_component	Golgi apparatus
G	0006561	biological_process	proline biosynthetic process
G	0006979	biological_process	response to oxidative stress
G	0008652	biological_process	amino acid biosynthetic process
G	0009414	biological_process	response to water deprivation
G	0009507	cellular_component	chloroplast
G	0009555	biological_process	pollen development
G	0009651	biological_process	response to salt stress
G	0010228	biological_process	vegetative to reproductive phase transition of meristem
G	0016301	molecular_function	kinase activity
G	0016491	molecular_function	oxidoreductase activity
G	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
G	0016740	molecular_function	transferase activity
G	0017084	molecular_function	delta1-pyrroline-5-carboxylate synthetase activity
G	0042538	biological_process	hyperosmotic salinity response
G	0048364	biological_process	root development
G	0055129	biological_process	L-proline biosynthetic process
H	0000166	molecular_function	nucleotide binding
H	0003824	molecular_function	catalytic activity
H	0004349	molecular_function	glutamate 5-kinase activity
H	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005794	cellular_component	Golgi apparatus
H	0006561	biological_process	proline biosynthetic process
H	0006979	biological_process	response to oxidative stress
H	0008652	biological_process	amino acid biosynthetic process
H	0009414	biological_process	response to water deprivation
H	0009507	cellular_component	chloroplast
H	0009555	biological_process	pollen development
H	0009651	biological_process	response to salt stress
H	0010228	biological_process	vegetative to reproductive phase transition of meristem
H	0016301	molecular_function	kinase activity
H	0016491	molecular_function	oxidoreductase activity
H	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
H	0016740	molecular_function	transferase activity
H	0017084	molecular_function	delta1-pyrroline-5-carboxylate synthetase activity
H	0042538	biological_process	hyperosmotic salinity response
H	0048364	biological_process	root development
H	0055129	biological_process	L-proline biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00902
Number of Residues	18
Details	GLUTAMATE_5_KINASE Glutamate 5-kinase signature. SrlGrGGMtAKVkAAvnA

Chain	Residue	Details
B	SER232-ALA249

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site_id	PS01223
Number of Residues	22
Details	PROA Gamma-glutamyl phosphate reductase signature. VedvygAIdHIhrHGSaHTDc.I

Chain	Residue	Details
B	VAL607-ILE628

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
B	SER60
A	ARG236
F	SER60
F	ASP157
F	ASN176
F	SER196
F	ARG236
C	SER60
C	ASP157
C	ASN176
C	SER196
B	ASP157
C	ARG236
G	SER60
G	ASP157
G	ASN176
G	SER196
G	ARG236
D	SER60
D	ASP157
D	ASN176
D	SER196
B	ASN176
D	ARG236
H	SER60
H	ASP157
H	ASN176
H	SER196
H	ARG236
E	SER60
E	ASP157
E	ASN176
E	SER196
B	SER196
E	ARG236
B	ARG236
A	SER60
A	ASP157
A	ASN176
A	SER196

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