8Y1E
3up-TM conformation of HKU1-B S protein after incubation of the receptor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| A | 0019031 | cellular_component | viral envelope |
| A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| A | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| A | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| A | 0055036 | cellular_component | virion membrane |
| A | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| B | 0016020 | cellular_component | membrane |
| B | 0019031 | cellular_component | viral envelope |
| B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| B | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| B | 0055036 | cellular_component | virion membrane |
| B | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| C | 0016020 | cellular_component | membrane |
| C | 0019031 | cellular_component | viral envelope |
| C | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| C | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| C | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| C | 0055036 | cellular_component | virion membrane |
| C | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0016020 | cellular_component | membrane |
| E | 0004252 | molecular_function | serine-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| E | 0016020 | cellular_component | membrane |
| F | 0004252 | molecular_function | serine-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
| F | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
| Chain | Residue | Details |
| D | VAL292-CYS297 |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| D | ASP435-VAL446 |
| site_id | PS01209 |
| Number of Residues | 23 |
| Details | LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CInpsnw.CDgvsHCpgg.EDEnr...C |
| Chain | Residue | Details |
| D | CYS126-CYS148 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000269|PubMed:11245484, ECO:0000269|PubMed:38964326 |
| Chain | Residue | Details |
| D | HIS296 | |
| E | HIS296 | |
| F | HIS296 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system => ECO:0000305|PubMed:38964326 |
| Chain | Residue | Details |
| D | ASP345 | |
| D | SER441 | |
| E | ASP345 | |
| E | SER441 | |
| F | ASP345 | |
| F | SER441 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 15 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:37990007, ECO:0000269|PubMed:38964326, ECO:0007744|PDB:7XYD, ECO:0007744|PDB:7Y0E, ECO:0007744|PDB:7Y0F, ECO:0007744|PDB:8HD8, ECO:0007744|PDB:8S0L |
| Chain | Residue | Details |
| D | ASN131 | |
| E | GLU145 | |
| F | ASN131 | |
| F | ASP134 | |
| F | VAL136 | |
| F | ASP144 | |
| F | GLU145 | |
| A | ASN684 | |
| A | ASN703 | |
| A | ASN725 | |
| A | ASN771 | |
| D | ASP134 | |
| A | ASN776 | |
| A | ASN793 | |
| A | ASN924 | |
| A | ASN1181 | |
| A | ASN1211 | |
| A | ASN1221 | |
| A | ASN1226 | |
| A | ASN1240 | |
| A | ASN1247 | |
| A | ASN1255 | |
| D | VAL136 | |
| A | ASN1276 | |
| B | ASN19 | |
| B | ASN29 | |
| B | ASN58 | |
| B | ASN114 | |
| B | ASN132 | |
| B | ASN171 | |
| B | ASN188 | |
| B | ASN192 | |
| B | ASN251 | |
| D | ASP144 | |
| B | ASN335 | |
| B | ASN355 | |
| B | ASN433 | |
| B | ASN454 | |
| B | ASN561 | |
| B | ASN664 | |
| B | ASN684 | |
| B | ASN703 | |
| B | ASN725 | |
| B | ASN771 | |
| D | GLU145 | |
| B | ASN776 | |
| B | ASN793 | |
| B | ASN924 | |
| B | ASN1181 | |
| B | ASN1211 | |
| B | ASN1221 | |
| B | ASN1226 | |
| B | ASN1240 | |
| B | ASN1247 | |
| B | ASN1255 | |
| E | ASN131 | |
| B | ASN1276 | |
| C | ASN19 | |
| C | ASN29 | |
| C | ASN58 | |
| C | ASN114 | |
| C | ASN132 | |
| C | ASN171 | |
| C | ASN188 | |
| C | ASN192 | |
| C | ASN251 | |
| E | ASP134 | |
| C | ASN335 | |
| C | ASN355 | |
| C | ASN433 | |
| C | ASN454 | |
| C | ASN561 | |
| C | ASN664 | |
| C | ASN684 | |
| C | ASN703 | |
| C | ASN725 | |
| C | ASN771 | |
| E | VAL136 | |
| C | ASN776 | |
| C | ASN793 | |
| C | ASN924 | |
| C | ASN1181 | |
| C | ASN1211 | |
| C | ASN1221 | |
| C | ASN1226 | |
| C | ASN1240 | |
| C | ASN1247 | |
| C | ASN1255 | |
| E | ASP144 | |
| C | ASN1276 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:11245484, ECO:0000269|PubMed:38964328 |
| Chain | Residue | Details |
| D | GLN255 | |
| E | GLN255 | |
| F | GLN255 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:37990007, ECO:0000269|PubMed:38964326, ECO:0007744|PDB:7XYD, ECO:0007744|PDB:7Y0E, ECO:0007744|PDB:7Y0F, ECO:0007744|PDB:8HD8, ECO:0007744|PDB:8S0L, ECO:0007744|PDB:8S0M |
| Chain | Residue | Details |
| D | ASN213 | |
| E | ASN213 | |
| F | ASN213 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| D | ASN249 | |
| E | ASN249 | |
| F | ASN249 |
