8XY7
hPhK alpha-gamma subcomplex in active state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004689 | molecular_function | phosphorylase kinase activity |
| A | 0005516 | molecular_function | calmodulin binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005964 | cellular_component | phosphorylase kinase complex |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0005977 | biological_process | glycogen metabolic process |
| A | 0005980 | biological_process | glycogen catabolic process |
| A | 0006091 | biological_process | generation of precursor metabolites and energy |
| A | 0045819 | biological_process | positive regulation of glycogen catabolic process |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0004674 | molecular_function | protein serine/threonine kinase activity |
| C | 0004689 | molecular_function | phosphorylase kinase activity |
| C | 0005516 | molecular_function | calmodulin binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0005964 | cellular_component | phosphorylase kinase complex |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0005977 | biological_process | glycogen metabolic process |
| C | 0005980 | biological_process | glycogen catabolic process |
| C | 0006468 | biological_process | protein phosphorylation |
| C | 0007165 | biological_process | signal transduction |
| C | 0019899 | molecular_function | enzyme binding |
| C | 0050321 | molecular_function | tau-protein kinase activity |
| C | 0106310 | molecular_function | protein serine kinase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGVSSVVRrCihkptsqe..........YAVK |
| Chain | Residue | Details |
| C | LEU26-LYS49 |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IvHrDLKpeNILL |
| Chain | Residue | Details |
| C | ILE146-LEU158 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Region: {"description":"Calmodulin-binding","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q64649","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Lipidation: {"description":"S-farnesyl cysteine","evidences":[{"source":"UniProtKB","id":"P18688","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
