Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8XVY

Cryo-EM structure of OSCA3.1-2E(R611E-R619E)-closed/open state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000325	cellular_component	plant-type vacuole
A	0003729	molecular_function	mRNA binding
A	0005227	molecular_function	calcium-activated cation channel activity
A	0005634	cellular_component	nucleus
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0008381	molecular_function	mechanosensitive monoatomic ion channel activity
A	0009506	cellular_component	plasmodesma
A	0009941	cellular_component	chloroplast envelope
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0098655	biological_process	monoatomic cation transmembrane transport
B	0000325	cellular_component	plant-type vacuole
B	0003729	molecular_function	mRNA binding
B	0005227	molecular_function	calcium-activated cation channel activity
B	0005634	cellular_component	nucleus
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0008381	molecular_function	mechanosensitive monoatomic ion channel activity
B	0009506	cellular_component	plasmodesma
B	0009941	cellular_component	chloroplast envelope
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0098655	biological_process	monoatomic cation transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=TM0","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	492
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	44
Details	Transmembrane: {"description":"Helical; Name=TM1","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	44
Details	Transmembrane: {"description":"Helical; Name=TM2","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	52
Details	Transmembrane: {"description":"Helical; Name=TM3","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	54
Details	Transmembrane: {"description":"Helical; Name=TM4","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	50
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	46
Details	Transmembrane: {"description":"Helical; Name=TM5","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	26
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	62
Details	Transmembrane: {"description":"Helical; Name=TM6","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	48
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	38
Details	Transmembrane: {"description":"Helical; Name=TM7","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	36
Details	Transmembrane: {"description":"Helical; Name=TM8","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	46
Details	Transmembrane: {"description":"Helical; Name=TM9","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	8
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=TM10","evidences":[{"source":"PubMed","id":"30190597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37402734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38592763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8GRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XVZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	136
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)