Functional Information from GO Data
| Chain | GOid | namespace | contents |
| R | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| R | 0004930 | molecular_function | G protein-coupled receptor activity |
| R | 0004962 | molecular_function | endothelin receptor activity |
| R | 0005506 | molecular_function | iron ion binding |
| R | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| R | 0008217 | biological_process | regulation of blood pressure |
| R | 0009055 | molecular_function | electron transfer activity |
| R | 0016020 | cellular_component | membrane |
| R | 0020037 | molecular_function | heme binding |
| R | 0022900 | biological_process | electron transport chain |
| R | 0042310 | biological_process | vasoconstriction |
| R | 0042597 | cellular_component | periplasmic space |
| R | 0046872 | molecular_function | metal ion binding |
| R | 0048484 | biological_process | enteric nervous system development |
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ITVlNLCALSVDRYRaV |
| Chain | Residue | Details |
| R | ILE171-VAL187 | |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR208-HIS214 | |
| L | TYR194-HIS200 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| R | ALA-131 | |
| Chain | Residue | Details |
| R | GLU-18 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| R | TYR81-LEU102 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 32 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| R | ARG103-ARG112 | |
| R | ASP182-GLU205 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| R | ASN113-ILE132 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 70 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| R | ASP133-LYS159 | |
| R | GLU230-ASP256 | |
| R | LYS329-LEU347 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| R | LEU160-VAL181 | |
| site_id | SWS_FT_FI8 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| R | ILE206-PHE229 | |
| site_id | SWS_FT_FI9 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| R | TRP257-MET278 | |
| site_id | SWS_FT_FI10 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| R | THR307-LEU328 | |
| site_id | SWS_FT_FI11 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| R | LEU348-VAL372 | |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| R | ASN62 | |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| R | TRP1012 | |
| R | ILE1107 | |
