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8XVG

Structure of human NuA4/TIP60 complex

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0000492biological_processbox C/D snoRNP assembly
A0000723biological_processtelomere maintenance
A0000786cellular_componentnucleosome
A0000812cellular_componentSwr1 complex
A0001094molecular_functionTFIID-class transcription factor complex binding
A0003678molecular_functionDNA helicase activity
A0003713molecular_functiontranscription coactivator activity
A0004386molecular_functionhelicase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005813cellular_componentcentrosome
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0006275biological_processregulation of DNA replication
A0006281biological_processDNA repair
A0006282biological_processregulation of DNA repair
A0006310biological_processDNA recombination
A0006325biological_processchromatin organization
A0006338biological_processchromatin remodeling
A0006355biological_processregulation of DNA-templated transcription
A0006357biological_processregulation of transcription by RNA polymerase II
A0007283biological_processspermatogenesis
A0016020cellular_componentmembrane
A0016363cellular_componentnuclear matrix
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0017025molecular_functionTBP-class protein binding
A0031011cellular_componentIno80 complex
A0032508biological_processDNA duplex unwinding
A0033044biological_processregulation of chromosome organization
A0035267cellular_componentNuA4 histone acetyltransferase complex
A0042981biological_processregulation of apoptotic process
A0043531molecular_functionADP binding
A0045296molecular_functioncadherin binding
A0045739biological_processpositive regulation of DNA repair
A0045893biological_processpositive regulation of DNA-templated transcription
A0045995biological_processregulation of embryonic development
A0050821biological_processprotein stabilization
A0051117molecular_functionATPase binding
A0051276biological_processchromosome organization
A0051301biological_processcell division
A0051726biological_processregulation of cell cycle
A0060382biological_processregulation of DNA strand elongation
A0070062cellular_componentextracellular exosome
A0071339cellular_componentMLL1 complex
A0090263biological_processpositive regulation of canonical Wnt signaling pathway
A0090671biological_processtelomerase RNA localization to Cajal body
A0097255cellular_componentR2TP complex
A0101031cellular_componentprotein folding chaperone complex
A0120293cellular_componentdynein axonemal particle
A1904507biological_processpositive regulation of telomere maintenance in response to DNA damage
A1905168biological_processpositive regulation of double-strand break repair via homologous recombination
A1990062cellular_componentRPAP3/R2TP/prefoldin-like complex
A1990904cellular_componentribonucleoprotein complex
A2000779biological_processregulation of double-strand break repair
B0000492biological_processbox C/D snoRNP assembly
B0000723biological_processtelomere maintenance
B0000786cellular_componentnucleosome
B0000791cellular_componenteuchromatin
B0000812cellular_componentSwr1 complex
B0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
B0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
B0001094molecular_functionTFIID-class transcription factor complex binding
B0003678molecular_functionDNA helicase activity
B0003714molecular_functiontranscription corepressor activity
B0004386molecular_functionhelicase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005813cellular_componentcentrosome
B0005829cellular_componentcytosol
B0006275biological_processregulation of DNA replication
B0006281biological_processDNA repair
B0006282biological_processregulation of DNA repair
B0006310biological_processDNA recombination
B0006325biological_processchromatin organization
B0006338biological_processchromatin remodeling
B0006355biological_processregulation of DNA-templated transcription
B0006357biological_processregulation of transcription by RNA polymerase II
B0006457biological_processprotein folding
B0008013molecular_functionbeta-catenin binding
B0016020cellular_componentmembrane
B0016363cellular_componentnuclear matrix
B0016787molecular_functionhydrolase activity
B0016887molecular_functionATP hydrolysis activity
B0017025molecular_functionTBP-class protein binding
B0031011cellular_componentIno80 complex
B0031490molecular_functionchromatin DNA binding
B0032508biological_processDNA duplex unwinding
B0033044biological_processregulation of chromosome organization
B0034644biological_processcellular response to UV
B0035267cellular_componentNuA4 histone acetyltransferase complex
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0042981biological_processregulation of apoptotic process
B0043531molecular_functionADP binding
B0045739biological_processpositive regulation of DNA repair
B0045892biological_processnegative regulation of DNA-templated transcription
B0045893biological_processpositive regulation of DNA-templated transcription
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0045995biological_processregulation of embryonic development
B0050821biological_processprotein stabilization
B0051082molecular_functionunfolded protein binding
B0051117molecular_functionATPase binding
B0051276biological_processchromosome organization
B0051726biological_processregulation of cell cycle
B0060382biological_processregulation of DNA strand elongation
B0070062cellular_componentextracellular exosome
B0071169biological_processestablishment of protein localization to chromatin
B0071339cellular_componentMLL1 complex
B0071392biological_processcellular response to estradiol stimulus
B0090090biological_processnegative regulation of canonical Wnt signaling pathway
B0090671biological_processtelomerase RNA localization to Cajal body
B0097255cellular_componentR2TP complex
B0101031cellular_componentprotein folding chaperone complex
B0120293cellular_componentdynein axonemal particle
B0140585molecular_functionpromoter-enhancer loop anchoring activity
B1904507biological_processpositive regulation of telomere maintenance in response to DNA damage
B1905168biological_processpositive regulation of double-strand break repair via homologous recombination
B1990062cellular_componentRPAP3/R2TP/prefoldin-like complex
B1990904cellular_componentribonucleoprotein complex
B2000779biological_processregulation of double-strand break repair
C0000492biological_processbox C/D snoRNP assembly
C0000723biological_processtelomere maintenance
C0000786cellular_componentnucleosome
C0000812cellular_componentSwr1 complex
C0001094molecular_functionTFIID-class transcription factor complex binding
C0003678molecular_functionDNA helicase activity
C0003713molecular_functiontranscription coactivator activity
C0004386molecular_functionhelicase activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005813cellular_componentcentrosome
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0006275biological_processregulation of DNA replication
C0006281biological_processDNA repair
C0006282biological_processregulation of DNA repair
C0006310biological_processDNA recombination
C0006325biological_processchromatin organization
C0006338biological_processchromatin remodeling
C0006355biological_processregulation of DNA-templated transcription
C0006357biological_processregulation of transcription by RNA polymerase II
C0007283biological_processspermatogenesis
C0016020cellular_componentmembrane
C0016363cellular_componentnuclear matrix
C0016787molecular_functionhydrolase activity
C0016887molecular_functionATP hydrolysis activity
C0017025molecular_functionTBP-class protein binding
C0031011cellular_componentIno80 complex
C0032508biological_processDNA duplex unwinding
C0033044biological_processregulation of chromosome organization
C0035267cellular_componentNuA4 histone acetyltransferase complex
C0042981biological_processregulation of apoptotic process
C0043531molecular_functionADP binding
C0045296molecular_functioncadherin binding
C0045739biological_processpositive regulation of DNA repair
C0045893biological_processpositive regulation of DNA-templated transcription
C0045995biological_processregulation of embryonic development
C0050821biological_processprotein stabilization
C0051117molecular_functionATPase binding
C0051276biological_processchromosome organization
C0051301biological_processcell division
C0051726biological_processregulation of cell cycle
C0060382biological_processregulation of DNA strand elongation
C0070062cellular_componentextracellular exosome
C0071339cellular_componentMLL1 complex
C0090263biological_processpositive regulation of canonical Wnt signaling pathway
C0090671biological_processtelomerase RNA localization to Cajal body
C0097255cellular_componentR2TP complex
C0101031cellular_componentprotein folding chaperone complex
C0120293cellular_componentdynein axonemal particle
C1904507biological_processpositive regulation of telomere maintenance in response to DNA damage
C1905168biological_processpositive regulation of double-strand break repair via homologous recombination
C1990062cellular_componentRPAP3/R2TP/prefoldin-like complex
C1990904cellular_componentribonucleoprotein complex
C2000779biological_processregulation of double-strand break repair
D0000492biological_processbox C/D snoRNP assembly
D0000723biological_processtelomere maintenance
D0000786cellular_componentnucleosome
D0000791cellular_componenteuchromatin
D0000812cellular_componentSwr1 complex
D0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
D0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
D0001094molecular_functionTFIID-class transcription factor complex binding
D0003678molecular_functionDNA helicase activity
D0003714molecular_functiontranscription corepressor activity
D0004386molecular_functionhelicase activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005813cellular_componentcentrosome
D0005829cellular_componentcytosol
D0006275biological_processregulation of DNA replication
D0006281biological_processDNA repair
D0006282biological_processregulation of DNA repair
D0006310biological_processDNA recombination
D0006325biological_processchromatin organization
D0006338biological_processchromatin remodeling
D0006355biological_processregulation of DNA-templated transcription
D0006357biological_processregulation of transcription by RNA polymerase II
D0006457biological_processprotein folding
D0008013molecular_functionbeta-catenin binding
D0016020cellular_componentmembrane
D0016363cellular_componentnuclear matrix
D0016787molecular_functionhydrolase activity
D0016887molecular_functionATP hydrolysis activity
D0017025molecular_functionTBP-class protein binding
D0031011cellular_componentIno80 complex
D0031490molecular_functionchromatin DNA binding
D0032508biological_processDNA duplex unwinding
D0033044biological_processregulation of chromosome organization
D0034644biological_processcellular response to UV
D0035267cellular_componentNuA4 histone acetyltransferase complex
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0042981biological_processregulation of apoptotic process
D0043531molecular_functionADP binding
D0045739biological_processpositive regulation of DNA repair
D0045892biological_processnegative regulation of DNA-templated transcription
D0045893biological_processpositive regulation of DNA-templated transcription
D0045944biological_processpositive regulation of transcription by RNA polymerase II
D0045995biological_processregulation of embryonic development
D0050821biological_processprotein stabilization
D0051082molecular_functionunfolded protein binding
D0051117molecular_functionATPase binding
D0051276biological_processchromosome organization
D0051726biological_processregulation of cell cycle
D0060382biological_processregulation of DNA strand elongation
D0070062cellular_componentextracellular exosome
D0071169biological_processestablishment of protein localization to chromatin
D0071339cellular_componentMLL1 complex
D0071392biological_processcellular response to estradiol stimulus
D0090090biological_processnegative regulation of canonical Wnt signaling pathway
D0090671biological_processtelomerase RNA localization to Cajal body
D0097255cellular_componentR2TP complex
D0101031cellular_componentprotein folding chaperone complex
D0120293cellular_componentdynein axonemal particle
D0140585molecular_functionpromoter-enhancer loop anchoring activity
D1904507biological_processpositive regulation of telomere maintenance in response to DNA damage
D1905168biological_processpositive regulation of double-strand break repair via homologous recombination
D1990062cellular_componentRPAP3/R2TP/prefoldin-like complex
D1990904cellular_componentribonucleoprotein complex
D2000779biological_processregulation of double-strand break repair
E0000492biological_processbox C/D snoRNP assembly
E0000723biological_processtelomere maintenance
E0000786cellular_componentnucleosome
E0000812cellular_componentSwr1 complex
E0001094molecular_functionTFIID-class transcription factor complex binding
E0003678molecular_functionDNA helicase activity
E0003713molecular_functiontranscription coactivator activity
E0004386molecular_functionhelicase activity
E0005515molecular_functionprotein binding
E0005524molecular_functionATP binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005737cellular_componentcytoplasm
E0005813cellular_componentcentrosome
E0005829cellular_componentcytosol
E0005856cellular_componentcytoskeleton
E0006275biological_processregulation of DNA replication
E0006281biological_processDNA repair
E0006282biological_processregulation of DNA repair
E0006310biological_processDNA recombination
E0006325biological_processchromatin organization
E0006338biological_processchromatin remodeling
E0006355biological_processregulation of DNA-templated transcription
E0006357biological_processregulation of transcription by RNA polymerase II
E0007283biological_processspermatogenesis
E0016020cellular_componentmembrane
E0016363cellular_componentnuclear matrix
E0016787molecular_functionhydrolase activity
E0016887molecular_functionATP hydrolysis activity
E0017025molecular_functionTBP-class protein binding
E0031011cellular_componentIno80 complex
E0032508biological_processDNA duplex unwinding
E0033044biological_processregulation of chromosome organization
E0035267cellular_componentNuA4 histone acetyltransferase complex
E0042981biological_processregulation of apoptotic process
E0043531molecular_functionADP binding
E0045296molecular_functioncadherin binding
E0045739biological_processpositive regulation of DNA repair
E0045893biological_processpositive regulation of DNA-templated transcription
E0045995biological_processregulation of embryonic development
E0050821biological_processprotein stabilization
E0051117molecular_functionATPase binding
E0051276biological_processchromosome organization
E0051301biological_processcell division
E0051726biological_processregulation of cell cycle
E0060382biological_processregulation of DNA strand elongation
E0070062cellular_componentextracellular exosome
E0071339cellular_componentMLL1 complex
E0090263biological_processpositive regulation of canonical Wnt signaling pathway
E0090671biological_processtelomerase RNA localization to Cajal body
E0097255cellular_componentR2TP complex
E0101031cellular_componentprotein folding chaperone complex
E0120293cellular_componentdynein axonemal particle
E1904507biological_processpositive regulation of telomere maintenance in response to DNA damage
E1905168biological_processpositive regulation of double-strand break repair via homologous recombination
E1990062cellular_componentRPAP3/R2TP/prefoldin-like complex
E1990904cellular_componentribonucleoprotein complex
E2000779biological_processregulation of double-strand break repair
F0000492biological_processbox C/D snoRNP assembly
F0000723biological_processtelomere maintenance
F0000786cellular_componentnucleosome
F0000791cellular_componenteuchromatin
F0000812cellular_componentSwr1 complex
F0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
F0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
F0001094molecular_functionTFIID-class transcription factor complex binding
F0003678molecular_functionDNA helicase activity
F0003714molecular_functiontranscription corepressor activity
F0004386molecular_functionhelicase activity
F0005515molecular_functionprotein binding
F0005524molecular_functionATP binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0005813cellular_componentcentrosome
F0005829cellular_componentcytosol
F0006275biological_processregulation of DNA replication
F0006281biological_processDNA repair
F0006282biological_processregulation of DNA repair
F0006310biological_processDNA recombination
F0006325biological_processchromatin organization
F0006338biological_processchromatin remodeling
F0006355biological_processregulation of DNA-templated transcription
F0006357biological_processregulation of transcription by RNA polymerase II
F0006457biological_processprotein folding
F0008013molecular_functionbeta-catenin binding
F0016020cellular_componentmembrane
F0016363cellular_componentnuclear matrix
F0016787molecular_functionhydrolase activity
F0016887molecular_functionATP hydrolysis activity
F0017025molecular_functionTBP-class protein binding
F0031011cellular_componentIno80 complex
F0031490molecular_functionchromatin DNA binding
F0032508biological_processDNA duplex unwinding
F0033044biological_processregulation of chromosome organization
F0034644biological_processcellular response to UV
F0035267cellular_componentNuA4 histone acetyltransferase complex
F0042802molecular_functionidentical protein binding
F0042803molecular_functionprotein homodimerization activity
F0042981biological_processregulation of apoptotic process
F0043531molecular_functionADP binding
F0045739biological_processpositive regulation of DNA repair
F0045892biological_processnegative regulation of DNA-templated transcription
F0045893biological_processpositive regulation of DNA-templated transcription
F0045944biological_processpositive regulation of transcription by RNA polymerase II
F0045995biological_processregulation of embryonic development
F0050821biological_processprotein stabilization
F0051082molecular_functionunfolded protein binding
F0051117molecular_functionATPase binding
F0051276biological_processchromosome organization
F0051726biological_processregulation of cell cycle
F0060382biological_processregulation of DNA strand elongation
F0070062cellular_componentextracellular exosome
F0071169biological_processestablishment of protein localization to chromatin
F0071339cellular_componentMLL1 complex
F0071392biological_processcellular response to estradiol stimulus
F0090090biological_processnegative regulation of canonical Wnt signaling pathway
F0090671biological_processtelomerase RNA localization to Cajal body
F0097255cellular_componentR2TP complex
F0101031cellular_componentprotein folding chaperone complex
F0120293cellular_componentdynein axonemal particle
F0140585molecular_functionpromoter-enhancer loop anchoring activity
F1904507biological_processpositive regulation of telomere maintenance in response to DNA damage
F1905168biological_processpositive regulation of double-strand break repair via homologous recombination
F1990062cellular_componentRPAP3/R2TP/prefoldin-like complex
F1990904cellular_componentribonucleoprotein complex
F2000779biological_processregulation of double-strand break repair
G0000122biological_processnegative regulation of transcription by RNA polymerase II
G0000786cellular_componentnucleosome
G0000812cellular_componentSwr1 complex
G0003714molecular_functiontranscription corepressor activity
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005654cellular_componentnucleoplasm
G0005657cellular_componentreplication fork
G0005694cellular_componentchromosome
G0005737cellular_componentcytoplasm
G0005829cellular_componentcytosol
G0006325biological_processchromatin organization
G0006338biological_processchromatin remodeling
G0006355biological_processregulation of DNA-templated transcription
G0035267cellular_componentNuA4 histone acetyltransferase complex
G0042307biological_processpositive regulation of protein import into nucleus
G0042981biological_processregulation of apoptotic process
G0045471biological_processresponse to ethanol
G0045892biological_processnegative regulation of DNA-templated transcription
G0045893biological_processpositive regulation of DNA-templated transcription
G0051726biological_processregulation of cell cycle
G0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
G1905168biological_processpositive regulation of double-strand break repair via homologous recombination
G2000779biological_processregulation of double-strand break repair
H0000786cellular_componentnucleosome
H0000812cellular_componentSwr1 complex
H0003677molecular_functionDNA binding
H0003682molecular_functionchromatin binding
H0004386molecular_functionhelicase activity
H0005515molecular_functionprotein binding
H0005524molecular_functionATP binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0006281biological_processDNA repair
H0006325biological_processchromatin organization
H0006338biological_processchromatin remodeling
H0016607cellular_componentnuclear speck
H0016787molecular_functionhydrolase activity
H0035267cellular_componentNuA4 histone acetyltransferase complex
H0042981biological_processregulation of apoptotic process
H0045893biological_processpositive regulation of DNA-templated transcription
H0051726biological_processregulation of cell cycle
H1905168biological_processpositive regulation of double-strand break repair via homologous recombination
H1990405molecular_functionprotein antigen binding
H2000779biological_processregulation of double-strand break repair
I0000723biological_processtelomere maintenance
I0000776cellular_componentkinetochore
I0000785cellular_componentchromatin
I0000786cellular_componentnucleosome
I0001825biological_processblastocyst formation
I0003407biological_processneural retina development
I0003682molecular_functionchromatin binding
I0003713molecular_functiontranscription coactivator activity
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005886cellular_componentplasma membrane
I0006275biological_processregulation of DNA replication
I0006281biological_processDNA repair
I0006282biological_processregulation of DNA repair
I0006310biological_processDNA recombination
I0006325biological_processchromatin organization
I0006338biological_processchromatin remodeling
I0006355biological_processregulation of DNA-templated transcription
I0006357biological_processregulation of transcription by RNA polymerase II
I0007165biological_processsignal transduction
I0007399biological_processnervous system development
I0008284biological_processpositive regulation of cell population proliferation
I0016363cellular_componentnuclear matrix
I0016514cellular_componentSWI/SNF complex
I0016586cellular_componentRSC-type complex
I0021510biological_processspinal cord development
I0030071biological_processregulation of mitotic metaphase/anaphase transition
I0031011cellular_componentIno80 complex
I0031492molecular_functionnucleosomal DNA binding
I0032991cellular_componentprotein-containing complex
I0033044biological_processregulation of chromosome organization
I0035060cellular_componentbrahma complex
I0035267cellular_componentNuA4 histone acetyltransferase complex
I0042981biological_processregulation of apoptotic process
I0045582biological_processpositive regulation of T cell differentiation
I0045596biological_processnegative regulation of cell differentiation
I0045597biological_processpositive regulation of cell differentiation
I0045663biological_processpositive regulation of myoblast differentiation
I0045739biological_processpositive regulation of DNA repair
I0045893biological_processpositive regulation of DNA-templated transcription
I0045995biological_processregulation of embryonic development
I0051726biological_processregulation of cell cycle
I0060382biological_processregulation of DNA strand elongation
I0070316biological_processregulation of G0 to G1 transition
I0071564cellular_componentnpBAF complex
I0140288cellular_componentGBAF complex
I1902459biological_processpositive regulation of stem cell population maintenance
I1904507biological_processpositive regulation of telomere maintenance in response to DNA damage
I1905168biological_processpositive regulation of double-strand break repair via homologous recombination
I2000045biological_processregulation of G1/S transition of mitotic cell cycle
I2000779biological_processregulation of double-strand break repair
I2000781biological_processpositive regulation of double-strand break repair
I2000819biological_processregulation of nucleotide-excision repair
J0000723biological_processtelomere maintenance
J0000776cellular_componentkinetochore
J0000785cellular_componentchromatin
J0000786cellular_componentnucleosome
J0001825biological_processblastocyst formation
J0003407biological_processneural retina development
J0003682molecular_functionchromatin binding
J0003713molecular_functiontranscription coactivator activity
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0005886cellular_componentplasma membrane
J0006275biological_processregulation of DNA replication
J0006281biological_processDNA repair
J0006282biological_processregulation of DNA repair
J0006310biological_processDNA recombination
J0006325biological_processchromatin organization
J0006338biological_processchromatin remodeling
J0006355biological_processregulation of DNA-templated transcription
J0006357biological_processregulation of transcription by RNA polymerase II
J0007165biological_processsignal transduction
J0007399biological_processnervous system development
J0008284biological_processpositive regulation of cell population proliferation
J0016363cellular_componentnuclear matrix
J0016514cellular_componentSWI/SNF complex
J0016586cellular_componentRSC-type complex
J0021510biological_processspinal cord development
J0030071biological_processregulation of mitotic metaphase/anaphase transition
J0031011cellular_componentIno80 complex
J0031492molecular_functionnucleosomal DNA binding
J0032991cellular_componentprotein-containing complex
J0033044biological_processregulation of chromosome organization
J0035060cellular_componentbrahma complex
J0035267cellular_componentNuA4 histone acetyltransferase complex
J0042981biological_processregulation of apoptotic process
J0045582biological_processpositive regulation of T cell differentiation
J0045596biological_processnegative regulation of cell differentiation
J0045597biological_processpositive regulation of cell differentiation
J0045663biological_processpositive regulation of myoblast differentiation
J0045739biological_processpositive regulation of DNA repair
J0045893biological_processpositive regulation of DNA-templated transcription
J0045995biological_processregulation of embryonic development
J0051726biological_processregulation of cell cycle
J0060382biological_processregulation of DNA strand elongation
J0070316biological_processregulation of G0 to G1 transition
J0071564cellular_componentnpBAF complex
J0140288cellular_componentGBAF complex
J1902459biological_processpositive regulation of stem cell population maintenance
J1904507biological_processpositive regulation of telomere maintenance in response to DNA damage
J1905168biological_processpositive regulation of double-strand break repair via homologous recombination
J2000045biological_processregulation of G1/S transition of mitotic cell cycle
J2000779biological_processregulation of double-strand break repair
J2000781biological_processpositive regulation of double-strand break repair
J2000819biological_processregulation of nucleotide-excision repair
L0000124cellular_componentSAGA complex
L0000786cellular_componentnucleosome
L0000812cellular_componentSwr1 complex
L0003712molecular_functiontranscription coregulator activity
L0005515molecular_functionprotein binding
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005794cellular_componentGolgi apparatus
L0006281biological_processDNA repair
L0006282biological_processregulation of DNA repair
L0006325biological_processchromatin organization
L0006355biological_processregulation of DNA-templated transcription
L0006357biological_processregulation of transcription by RNA polymerase II
L0016301molecular_functionkinase activity
L0019219biological_processregulation of nucleobase-containing compound metabolic process
L0033276cellular_componenttranscription factor TFTC complex
L0035267cellular_componentNuA4 histone acetyltransferase complex
L0042981biological_processregulation of apoptotic process
L0043484biological_processregulation of RNA splicing
L0045893biological_processpositive regulation of DNA-templated transcription
L0051726biological_processregulation of cell cycle
L0080135biological_processregulation of cellular response to stress
L1905168biological_processpositive regulation of double-strand break repair via homologous recombination
L2000779biological_processregulation of double-strand break repair
M0000122biological_processnegative regulation of transcription by RNA polymerase II
M0000724biological_processdouble-strand break repair via homologous recombination
M0000786cellular_componentnucleosome
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0005654cellular_componentnucleoplasm
M0005730cellular_componentnucleolus
M0005737cellular_componentcytoplasm
M0006325biological_processchromatin organization
M0006351biological_processDNA-templated transcription
M0006357biological_processregulation of transcription by RNA polymerase II
M0007283biological_processspermatogenesis
M0007286biological_processspermatid development
M0016604cellular_componentnuclear body
M0030154biological_processcell differentiation
M0031965cellular_componentnuclear membrane
M0032777cellular_componentpiccolo histone acetyltransferase complex
M0035092biological_processsperm DNA condensation
M0035267cellular_componentNuA4 histone acetyltransferase complex
M0035861cellular_componentsite of double-strand break
M0042981biological_processregulation of apoptotic process
M0045814biological_processnegative regulation of gene expression, epigenetic
M0045892biological_processnegative regulation of DNA-templated transcription
M0045893biological_processpositive regulation of DNA-templated transcription
M0045944biological_processpositive regulation of transcription by RNA polymerase II
M0051726biological_processregulation of cell cycle
M0140463molecular_functionchromatin-protein adaptor activity
M0140767molecular_functionenzyme-substrate adaptor activity
M1905168biological_processpositive regulation of double-strand break repair via homologous recombination
M2000779biological_processregulation of double-strand break repair
N0000122biological_processnegative regulation of transcription by RNA polymerase II
N0000786cellular_componentnucleosome
N0003677molecular_functionDNA binding
N0005515molecular_functionprotein binding
N0005634cellular_componentnucleus
N0005654cellular_componentnucleoplasm
N0006325biological_processchromatin organization
N0006338biological_processchromatin remodeling
N0006355biological_processregulation of DNA-templated transcription
N0016607cellular_componentnuclear speck
N0032991cellular_componentprotein-containing complex
N0035019biological_processsomatic stem cell population maintenance
N0035267cellular_componentNuA4 histone acetyltransferase complex
N0042393molecular_functionhistone binding
N0042981biological_processregulation of apoptotic process
N0045815biological_processtranscription initiation-coupled chromatin remodeling
N0045893biological_processpositive regulation of DNA-templated transcription
N0051726biological_processregulation of cell cycle
N0140713molecular_functionhistone chaperone activity
N1905168biological_processpositive regulation of double-strand break repair via homologous recombination
N2000779biological_processregulation of double-strand break repair
Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LILDSGATHTTA
ChainResidueDetails
ILEU168-ALA179

site_idPS00196
Number of Residues15
DetailsCOPPER_BLUE Type-1 copper (blue) proteins signature. GeiSpFLCs.GsHqv..Q
ChainResidueDetails
LGLY2632-GLN2646

site_idPS00406
Number of Residues11
DetailsACTINS_1 Actins signature 1. YVGDEAQs.KRG
ChainResidueDetails
KTYR53-GLY63

site_idPS00432
Number of Residues9
DetailsACTINS_2 Actins signature 2. WISKqEYDE
ChainResidueDetails
KTRP356-GLU364
ITRP410-GLU418

site_idPS01132
Number of Residues13
DetailsACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR
ChainResidueDetails
KLEU104-ARG116

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
MSER539
JSER2
FGLY77

site_idSWS_FT_FI2
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
MLYS319
JSER86
MGLY673
HSER321
HALA755
HGLY928
HMET1011

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
ISER233
JSER233
GLYS214

site_idSWS_FT_FI4
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ILYS62
FLYS444
FLYS456
HALA1728
JLYS62
BLYS456
DLYS9
ELYS445
DLYS444
DLYS456
FLYS9

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648
ChainResidueDetails
HLEU945
CLYS225
ELYS225

site_idSWS_FT_FI6
Number of Residues3
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
HILE1472
HGLU2349
HILE2356

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
HALA1547
HVAL2686

site_idSWS_FT_FI8
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
HVAL2813

226707

PDB entries from 2024-10-30

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