Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8XVB

Cryo-EM structure of ATP-DNA-MuB filaments

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003677	molecular_function	DNA binding
A	0005524	molecular_function	ATP binding
A	0006260	biological_process	DNA replication
A	0006313	biological_process	DNA transposition
A	0015074	biological_process	DNA integration
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0030430	cellular_component	host cell cytoplasm
A	0032196	biological_process	transposition
A	0039693	biological_process	viral DNA genome replication
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0003677	molecular_function	DNA binding
B	0005524	molecular_function	ATP binding
B	0006260	biological_process	DNA replication
B	0006313	biological_process	DNA transposition
B	0015074	biological_process	DNA integration
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0030430	cellular_component	host cell cytoplasm
B	0032196	biological_process	transposition
B	0039693	biological_process	viral DNA genome replication
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0003677	molecular_function	DNA binding
C	0005524	molecular_function	ATP binding
C	0006260	biological_process	DNA replication
C	0006313	biological_process	DNA transposition
C	0015074	biological_process	DNA integration
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0030430	cellular_component	host cell cytoplasm
C	0032196	biological_process	transposition
C	0039693	biological_process	viral DNA genome replication
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0003677	molecular_function	DNA binding
D	0005524	molecular_function	ATP binding
D	0006260	biological_process	DNA replication
D	0006313	biological_process	DNA transposition
D	0015074	biological_process	DNA integration
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0030430	cellular_component	host cell cytoplasm
D	0032196	biological_process	transposition
D	0039693	biological_process	viral DNA genome replication
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0003677	molecular_function	DNA binding
E	0005524	molecular_function	ATP binding
E	0006260	biological_process	DNA replication
E	0006313	biological_process	DNA transposition
E	0015074	biological_process	DNA integration
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0030430	cellular_component	host cell cytoplasm
E	0032196	biological_process	transposition
E	0039693	biological_process	viral DNA genome replication
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0003677	molecular_function	DNA binding
F	0005524	molecular_function	ATP binding
F	0006260	biological_process	DNA replication
F	0006313	biological_process	DNA transposition
F	0015074	biological_process	DNA integration
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0030430	cellular_component	host cell cytoplasm
F	0032196	biological_process	transposition
F	0039693	biological_process	viral DNA genome replication
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0003677	molecular_function	DNA binding
G	0005524	molecular_function	ATP binding
G	0006260	biological_process	DNA replication
G	0006313	biological_process	DNA transposition
G	0015074	biological_process	DNA integration
G	0016787	molecular_function	hydrolase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0030430	cellular_component	host cell cytoplasm
G	0032196	biological_process	transposition
G	0039693	biological_process	viral DNA genome replication
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0003677	molecular_function	DNA binding
H	0005524	molecular_function	ATP binding
H	0006260	biological_process	DNA replication
H	0006313	biological_process	DNA transposition
H	0015074	biological_process	DNA integration
H	0016787	molecular_function	hydrolase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0030430	cellular_component	host cell cytoplasm
H	0032196	biological_process	transposition
H	0039693	biological_process	viral DNA genome replication
H	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	152
Details	DNA_BIND: H-T-H motif => ECO:0000255

Chain	Residue	Details
A	PHE21-ASN40
B	PHE21-ASN40
C	PHE21-ASN40
D	PHE21-ASN40
E	PHE21-ASN40
F	PHE21-ASN40
G	PHE21-ASN40
H	PHE21-ASN40

site_id	SWS_FT_FI2
Number of Residues	712
Details	DNA_BIND:

Chain	Residue	Details
A	SER223-ASN312
B	SER223-ASN312
C	SER223-ASN312
D	SER223-ASN312
E	SER223-ASN312
F	SER223-ASN312
G	SER223-ASN312
H	SER223-ASN312

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY100
B	GLY100
C	GLY100
D	GLY100
E	GLY100
F	GLY100
G	GLY100
H	GLY100

site_id	SWS_FT_FI4
Number of Residues	16
Details	SITE: Involved in DNA binding => ECO:0000269\|PubMed:23776210

Chain	Residue	Details
A	ARG151
E	LYS152
F	ARG151
F	LYS152
G	ARG151
G	LYS152
H	ARG151
H	LYS152
A	LYS152
B	ARG151
B	LYS152
C	ARG151
C	LYS152
D	ARG151
D	LYS152
E	ARG151

site_id	SWS_FT_FI5
Number of Residues	8
Details	SITE: Sensor-1; involved in ATP-binding and hydrolysis => ECO:0000269\|PubMed:23776210

Chain	Residue	Details
A	ASN202
B	ASN202
C	ASN202
D	ASN202
E	ASN202
F	ASN202
G	ASN202
H	ASN202

site_id	SWS_FT_FI6
Number of Residues	8
Details	SITE: R-finger; involved in ATP-binding => ECO:0000269\|PubMed:23776210

Chain	Residue	Details
A	ARG224
B	ARG224
C	ARG224
D	ARG224
E	ARG224
F	ARG224
G	ARG224
H	ARG224

site_id	SWS_FT_FI7
Number of Residues	8
Details	SITE: Sensor-2; involved in ATP-binding and hydrolysis => ECO:0000269\|PubMed:23776210

Chain	Residue	Details
A	ARG268
B	ARG268
C	ARG268
D	ARG268
E	ARG268
F	ARG268
G	ARG268
H	ARG268

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)