8XRF
The crystal structure of AsfvTopII in complex with G-DNA
Functional Information from PROSITE/UniProt
| site_id | PS00177 |
| Number of Residues | 9 |
| Details | TOPOISOMERASE_II DNA topoisomerase II signature. AAEGDSALS |
| Chain | Residue | Details |
| A | ALA436-SER444 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: O-(5'-phospho-DNA)-tyrosine intermediate => ECO:0000255|PROSITE-ProRule:PRU01384, ECO:0000303|PubMed:25463606 |
| Chain | Residue | Details |
| A | TYR800 | |
| B | TYR800 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P11388 |
| Chain | Residue | Details |
| A | GLU438 | |
| A | ASP539 | |
| A | ASP541 | |
| B | GLU438 | |
| B | ASP539 | |
| B | ASP541 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG799 | |
| B | ARG799 |
