8XPN
The Crystal Structure of USP8 from Biortus.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| B | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| B | 0016579 | biological_process | protein deubiquitination |
| C | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| C | 0016579 | biological_process | protein deubiquitination |
Functional Information from PROSITE/UniProt
| site_id | PS00304 |
| Number of Residues | 10 |
| Details | SASP_1 Small, acid-soluble spore proteins, alpha/beta type, signature 1. KgEVAeEFGI |
| Chain | Residue | Details |
| A | LYS823-ILE832 |
| site_id | PS00972 |
| Number of Residues | 16 |
| Details | USP_1 Ubiquitin specific protease (USP) domain signature 1. GLrnlGNtCYMNSiLQ |
| Chain | Residue | Details |
| A | GLY778-GLN793 |
| site_id | PS00973 |
| Number of Residues | 18 |
| Details | USP_2 Ubiquitin specific protease (USP) domain signature 2. YnLfSVsnHyGgldg..GHY |
| Chain | Residue | Details |
| A | TYR1051-TYR1068 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU10092","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10093","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10092","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10093","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q80U87","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
