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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8XOB

VMAT2 protonated state

Functional Information from GO Data
ChainGOidnamespacecontents
A0022857molecular_functiontransmembrane transporter activity
A0055085biological_processtransmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues42
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues43
DetailsTopological domain: {"description":"Lumenal, vesicle","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues22
DetailsTransmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues22
DetailsTransmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues19
DetailsTransmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues23
DetailsTransmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=10","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=11","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues21
DetailsTransmembrane: {"description":"Helical; Name=12","evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38517752","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8JTC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T69","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8THR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues3
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI19
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"37914936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38081299","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8T6B","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

239149

PDB entries from 2025-07-23

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