8XFV
Crystal structure of human Golgi resident glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-(piperidin-4-yloxy)indolin-2-one
This is a non-PDB format compatible entry.
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:Q16769 |
| Chain | Residue | Details |
| X | GLU225 | |
| D | ASP269 | |
| E | GLU225 | |
| E | ASP269 | |
| F | GLU225 | |
| F | ASP269 | |
| G | GLU225 | |
| G | ASP269 | |
| H | GLU225 | |
| H | ASP269 | |
| I | GLU225 | |
| X | ASP269 | |
| I | ASP269 | |
| J | GLU225 | |
| J | ASP269 | |
| A | GLU225 | |
| A | ASP269 | |
| B | GLU225 | |
| B | ASP269 | |
| C | GLU225 | |
| C | ASP269 | |
| D | GLU225 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 33 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q16769 |
| Chain | Residue | Details |
| X | ASP186 | |
| C | ASP186 | |
| C | GLU226 | |
| C | HIS351 | |
| D | ASP186 | |
| D | GLU226 | |
| D | HIS351 | |
| E | ASP186 | |
| E | GLU226 | |
| E | HIS351 | |
| F | ASP186 | |
| X | GLU226 | |
| F | GLU226 | |
| F | HIS351 | |
| G | ASP186 | |
| G | GLU226 | |
| G | HIS351 | |
| H | ASP186 | |
| H | GLU226 | |
| H | HIS351 | |
| I | ASP186 | |
| I | GLU226 | |
| X | HIS351 | |
| I | HIS351 | |
| J | ASP186 | |
| J | GLU226 | |
| J | HIS351 | |
| A | ASP186 | |
| A | GLU226 | |
| A | HIS351 | |
| B | ASP186 | |
| B | GLU226 | |
| B | HIS351 |
