8XDF

Cryo-EM structure of human urea transporter B.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005372	molecular_function	water transmembrane transporter activity
A	0005886	cellular_component	plasma membrane
A	0006833	biological_process	water transport
A	0015204	molecular_function	urea transmembrane transporter activity
A	0015265	molecular_function	urea channel activity
A	0015840	biological_process	urea transport
A	0016020	cellular_component	membrane
A	0016323	cellular_component	basolateral plasma membrane
A	0051649	biological_process	establishment of localization in cell
A	0055085	biological_process	transmembrane transport
A	0071918	biological_process	urea transmembrane transport
B	0005372	molecular_function	water transmembrane transporter activity
B	0005886	cellular_component	plasma membrane
B	0006833	biological_process	water transport
B	0015204	molecular_function	urea transmembrane transporter activity
B	0015265	molecular_function	urea channel activity
B	0015840	biological_process	urea transport
B	0016020	cellular_component	membrane
B	0016323	cellular_component	basolateral plasma membrane
B	0051649	biological_process	establishment of localization in cell
B	0055085	biological_process	transmembrane transport
B	0071918	biological_process	urea transmembrane transport
C	0005372	molecular_function	water transmembrane transporter activity
C	0005886	cellular_component	plasma membrane
C	0006833	biological_process	water transport
C	0015204	molecular_function	urea transmembrane transporter activity
C	0015265	molecular_function	urea channel activity
C	0015840	biological_process	urea transport
C	0016020	cellular_component	membrane
C	0016323	cellular_component	basolateral plasma membrane
C	0051649	biological_process	establishment of localization in cell
C	0055085	biological_process	transmembrane transport
C	0071918	biological_process	urea transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00079
Number of Residues	21
Details	MULTICOPPER_OXIDASE1 Multicopper oxidases signature 1. GlWgFnSsLAciAmGGMfmaL

Chain	Residue	Details
A	GLY284-LEU304

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	537
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	3
Details	Site: {"description":"Important for channel permeability","evidences":[{"source":"UniProtKB","id":"Q5QF96","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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