8XBG

Human GPR34 -Gi complex bound to S3E-LysoPS, receptor focused

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004930	molecular_function	G protein-coupled receptor activity
A	0005886	cellular_component	plasma membrane
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0035589	biological_process	G protein-coupled purinergic nucleotide receptor signaling pathway
A	0045028	molecular_function	G protein-coupled purinergic nucleotide receptor activity

Functional Information from PROSITE/UniProt

site_id	PS00237
Number of Residues	17
Details	G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ISIiLLGFISLDRYIkI

Chain	Residue	Details
A	ILE140-ILE156

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:27086875

Chain	Residue	Details
A	SER62-ILE82

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site_id	SWS_FT_FI2
Number of Residues	106
Details	TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:27086875

Chain	Residue	Details
A	HIS83-SER88
A	LEU150-SER171
A	TYR238-PHE269
A	SER332-THR381

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site_id	SWS_FT_FI3
Number of Residues	20
Details	TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:27086875

Chain	Residue	Details
A	ILE89-PHE109

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site_id	SWS_FT_FI4
Number of Residues	60
Details	TOPO_DOM: Extracellular => ECO:0000269|PubMed:27086875

Chain	Residue	Details
A	ARG110-LYS128
A	THR193-GLU216
A	SER291-GLU310

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site_id	SWS_FT_FI5
Number of Residues	20
Details	TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:27086875

Chain	Residue	Details
A	VAL129-SER149

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site_id	SWS_FT_FI6
Number of Residues	20
Details	TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:27086875

Chain	Residue	Details
A	ILE172-LEU192

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site_id	SWS_FT_FI7
Number of Residues	20
Details	TRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:27086875

Chain	Residue	Details
A	ALA217-SER237

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site_id	SWS_FT_FI8
Number of Residues	20
Details	TRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:27086875

Chain	Residue	Details
A	ILE270-ILE290

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site_id	SWS_FT_FI9
Number of Residues	20
Details	TRANSMEM: Helical; Name=7 => ECO:0000269|PubMed:27086875

Chain	Residue	Details
A	ILE311-SER331

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site_id	SWS_FT_FI10
Number of Residues	5
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN28
A	ASN36
A	ASN42
A	ASN200
A	ASN295

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