8X55
BA.2.86 Spike Trimer with T356K mutation (3 RBD down)
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | GLN690 | |
| B | GLN690 | |
| C | GLN690 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | ASP820 | |
| B | ASP820 | |
| C | ASP820 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | PRO17 | |
| A | ASP1163 | |
| A | ASN1178 | |
| B | PRO17 | |
| B | ASP1163 | |
| B | ASN1178 | |
| C | PRO17 | |
| C | ASP1163 | |
| C | ASN1178 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN61 | |
| B | PRO1079 | |
| C | ASN61 | |
| C | THR124 | |
| C | VAL722 | |
| C | LEU806 | |
| C | PRO1079 | |
| A | THR124 | |
| A | VAL722 | |
| A | LEU806 | |
| A | PRO1079 | |
| B | ASN61 | |
| B | THR124 | |
| B | VAL722 | |
| B | LEU806 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | THR76 | |
| A | TRP152 | |
| A | ASP1199 | |
| B | THR76 | |
| B | TRP152 | |
| B | ASP1199 | |
| C | THR76 | |
| C | TRP152 | |
| C | ASP1199 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 21 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | PHE168 | |
| B | LEU335 | |
| B | PHE347 | |
| B | SER621 | |
| B | CYS662 | |
| B | PHE1103 | |
| C | PHE168 | |
| C | THR286 | |
| C | LEU335 | |
| C | PHE347 | |
| C | SER621 | |
| A | THR286 | |
| C | CYS662 | |
| C | PHE1103 | |
| A | LEU335 | |
| A | PHE347 | |
| A | SER621 | |
| A | CYS662 | |
| A | PHE1103 | |
| B | PHE168 | |
| B | THR286 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | PHE238 | |
| A | ILE714 | |
| B | PHE238 | |
| B | ILE714 | |
| C | PHE238 | |
| C | ILE714 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | VAL327 | |
| B | VAL327 | |
| C | VAL327 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | PHE329 | |
| B | PHE329 | |
| C | PHE329 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | VAL608 | |
| B | VAL608 | |
| C | VAL608 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
| Chain | Residue | Details |
| A | ARG681 | |
| A | ALA683 | |
| B | ARG681 | |
| B | ALA683 | |
| C | ARG681 | |
| C | ALA683 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASP1139 | |
| B | ASP1139 | |
| C | ASP1139 |
