8X1C

Structure of nucleosome-bound SRCAP-C in the ADP-bound state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000786	cellular_component	nucleosome
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0006325	biological_process	chromatin organization
A	0008285	biological_process	negative regulation of cell population proliferation
A	0030527	molecular_function	structural constituent of chromatin
A	0031507	biological_process	heterochromatin formation
A	0046982	molecular_function	protein heterodimerization activity
A	0070062	cellular_component	extracellular exosome
B	0000786	cellular_component	nucleosome
B	0002227	biological_process	innate immune response in mucosa
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0005615	cellular_component	extracellular space
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005694	cellular_component	chromosome
B	0006325	biological_process	chromatin organization
B	0006334	biological_process	nucleosome assembly
B	0019731	biological_process	antibacterial humoral response
B	0030527	molecular_function	structural constituent of chromatin
B	0042742	biological_process	defense response to bacterium
B	0042802	molecular_function	identical protein binding
B	0046982	molecular_function	protein heterodimerization activity
B	0050830	biological_process	defense response to Gram-positive bacterium
B	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
B	0070062	cellular_component	extracellular exosome
C	0000786	cellular_component	nucleosome
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005694	cellular_component	chromosome
C	0006325	biological_process	chromatin organization
C	0006334	biological_process	nucleosome assembly
C	0016020	cellular_component	membrane
C	0030527	molecular_function	structural constituent of chromatin
C	0031492	molecular_function	nucleosomal DNA binding
C	0031507	biological_process	heterochromatin formation
C	0032200	biological_process	telomere organization
C	0032991	cellular_component	protein-containing complex
C	0040029	biological_process	epigenetic regulation of gene expression
C	0045296	molecular_function	cadherin binding
C	0046982	molecular_function	protein heterodimerization activity
C	0070062	cellular_component	extracellular exosome
D	0000781	cellular_component	chromosome, telomeric region
D	0000786	cellular_component	nucleosome
D	0003677	molecular_function	DNA binding
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005694	cellular_component	chromosome
D	0006325	biological_process	chromatin organization
D	0006334	biological_process	nucleosome assembly
D	0016020	cellular_component	membrane
D	0030527	molecular_function	structural constituent of chromatin
D	0032200	biological_process	telomere organization
D	0032991	cellular_component	protein-containing complex
D	0043505	cellular_component	CENP-A containing nucleosome
D	0045653	biological_process	negative regulation of megakaryocyte differentiation
D	0046982	molecular_function	protein heterodimerization activity
D	0061644	biological_process	protein localization to CENP-A containing chromatin
D	0070062	cellular_component	extracellular exosome
E	0000786	cellular_component	nucleosome
E	0003677	molecular_function	DNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005694	cellular_component	chromosome
E	0006325	biological_process	chromatin organization
E	0008285	biological_process	negative regulation of cell population proliferation
E	0030527	molecular_function	structural constituent of chromatin
E	0031507	biological_process	heterochromatin formation
E	0046982	molecular_function	protein heterodimerization activity
E	0070062	cellular_component	extracellular exosome
F	0000786	cellular_component	nucleosome
F	0002227	biological_process	innate immune response in mucosa
F	0003677	molecular_function	DNA binding
F	0005515	molecular_function	protein binding
F	0005615	cellular_component	extracellular space
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005694	cellular_component	chromosome
F	0006325	biological_process	chromatin organization
F	0006334	biological_process	nucleosome assembly
F	0019731	biological_process	antibacterial humoral response
F	0030527	molecular_function	structural constituent of chromatin
F	0042742	biological_process	defense response to bacterium
F	0042802	molecular_function	identical protein binding
F	0046982	molecular_function	protein heterodimerization activity
F	0050830	biological_process	defense response to Gram-positive bacterium
F	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
F	0070062	cellular_component	extracellular exosome
G	0000786	cellular_component	nucleosome
G	0003677	molecular_function	DNA binding
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005694	cellular_component	chromosome
G	0006325	biological_process	chromatin organization
G	0006334	biological_process	nucleosome assembly
G	0016020	cellular_component	membrane
G	0030527	molecular_function	structural constituent of chromatin
G	0031492	molecular_function	nucleosomal DNA binding
G	0031507	biological_process	heterochromatin formation
G	0032200	biological_process	telomere organization
G	0032991	cellular_component	protein-containing complex
G	0040029	biological_process	epigenetic regulation of gene expression
G	0045296	molecular_function	cadherin binding
G	0046982	molecular_function	protein heterodimerization activity
G	0070062	cellular_component	extracellular exosome
H	0000781	cellular_component	chromosome, telomeric region
H	0000786	cellular_component	nucleosome
H	0003677	molecular_function	DNA binding
H	0003723	molecular_function	RNA binding
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005694	cellular_component	chromosome
H	0006325	biological_process	chromatin organization
H	0006334	biological_process	nucleosome assembly
H	0016020	cellular_component	membrane
H	0030527	molecular_function	structural constituent of chromatin
H	0032200	biological_process	telomere organization
H	0032991	cellular_component	protein-containing complex
H	0043505	cellular_component	CENP-A containing nucleosome
H	0045653	biological_process	negative regulation of megakaryocyte differentiation
H	0046982	molecular_function	protein heterodimerization activity
H	0061644	biological_process	protein localization to CENP-A containing chromatin
H	0070062	cellular_component	extracellular exosome
I	0000166	molecular_function	nucleotide binding
I	0000786	cellular_component	nucleosome
I	0000812	cellular_component	Swr1 complex
I	0003677	molecular_function	DNA binding
I	0003713	molecular_function	transcription coactivator activity
I	0004386	molecular_function	helicase activity
I	0005524	molecular_function	ATP binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0006325	biological_process	chromatin organization
I	0006338	biological_process	chromatin remodeling
I	0006355	biological_process	regulation of DNA-templated transcription
I	0010468	biological_process	regulation of gene expression
I	0010557	biological_process	positive regulation of macromolecule biosynthetic process
I	0016604	cellular_component	nuclear body
I	0016787	molecular_function	hydrolase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0032991	cellular_component	protein-containing complex
I	0042393	molecular_function	histone binding
I	0045944	biological_process	positive regulation of transcription by RNA polymerase II
I	0048471	cellular_component	perinuclear region of cytoplasm
I	0140096	molecular_function	catalytic activity, acting on a protein
I	0140658	molecular_function	ATP-dependent chromatin remodeler activity
I	0141156	biological_process	cAMP/PKA signal transduction
J	0000122	biological_process	negative regulation of transcription by RNA polymerase II
J	0000786	cellular_component	nucleosome
J	0000812	cellular_component	Swr1 complex
J	0003677	molecular_function	DNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0006325	biological_process	chromatin organization
J	0006338	biological_process	chromatin remodeling
J	0006355	biological_process	regulation of DNA-templated transcription
J	0016607	cellular_component	nuclear speck
J	0032991	cellular_component	protein-containing complex
J	0035267	cellular_component	NuA4 histone acetyltransferase complex
J	0042393	molecular_function	histone binding
J	0042981	biological_process	regulation of apoptotic process
J	0045815	biological_process	transcription initiation-coupled chromatin remodeling
J	0045893	biological_process	positive regulation of DNA-templated transcription
J	0051726	biological_process	regulation of cell cycle
J	0140713	molecular_function	histone chaperone activity
J	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
J	2000779	biological_process	regulation of double-strand break repair
K	0000786	cellular_component	nucleosome
K	0000812	cellular_component	Swr1 complex
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005730	cellular_component	nucleolus
K	0005856	cellular_component	cytoskeleton
K	0006338	biological_process	chromatin remodeling
K	0006355	biological_process	regulation of DNA-templated transcription
K	0007000	biological_process	nucleolus organization
K	0016479	biological_process	negative regulation of transcription by RNA polymerase I
K	0031491	molecular_function	nucleosome binding
K	0045943	biological_process	positive regulation of transcription by RNA polymerase I
L	0000786	cellular_component	nucleosome
L	0000812	cellular_component	Swr1 complex
L	0003015	biological_process	heart process
L	0003682	molecular_function	chromatin binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0006325	biological_process	chromatin organization
L	0006338	biological_process	chromatin remodeling
L	0006355	biological_process	regulation of DNA-templated transcription
L	0008270	molecular_function	zinc ion binding
L	0031491	molecular_function	nucleosome binding
L	0036335	biological_process	intestinal stem cell homeostasis
L	0042393	molecular_function	histone binding
L	0042692	biological_process	muscle cell differentiation
L	0042826	molecular_function	histone deacetylase binding
L	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
L	0045815	biological_process	transcription initiation-coupled chromatin remodeling
L	0046872	molecular_function	metal ion binding
L	0055074	biological_process	calcium ion homeostasis
L	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
L	0061484	biological_process	hematopoietic stem cell homeostasis
L	1905458	biological_process	positive regulation of lymphoid progenitor cell differentiation
M	0000166	molecular_function	nucleotide binding
M	0000492	biological_process	box C/D snoRNP assembly
M	0000723	biological_process	telomere maintenance
M	0000786	cellular_component	nucleosome
M	0000812	cellular_component	Swr1 complex
M	0001094	molecular_function	TFIID-class transcription factor complex binding
M	0003678	molecular_function	DNA helicase activity
M	0003713	molecular_function	transcription coactivator activity
M	0004386	molecular_function	helicase activity
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005813	cellular_component	centrosome
M	0005829	cellular_component	cytosol
M	0006275	biological_process	regulation of DNA replication
M	0006281	biological_process	DNA repair
M	0006282	biological_process	regulation of DNA repair
M	0006310	biological_process	DNA recombination
M	0006325	biological_process	chromatin organization
M	0006338	biological_process	chromatin remodeling
M	0006355	biological_process	regulation of DNA-templated transcription
M	0006357	biological_process	regulation of transcription by RNA polymerase II
M	0006974	biological_process	DNA damage response
M	0007283	biological_process	spermatogenesis
M	0008094	molecular_function	ATP-dependent activity, acting on DNA
M	0016020	cellular_component	membrane
M	0016363	cellular_component	nuclear matrix
M	0016607	cellular_component	nuclear speck
M	0016787	molecular_function	hydrolase activity
M	0016887	molecular_function	ATP hydrolysis activity
M	0017025	molecular_function	TBP-class protein binding
M	0031011	cellular_component	Ino80 complex
M	0033044	biological_process	regulation of chromosome organization
M	0035267	cellular_component	NuA4 histone acetyltransferase complex
M	0036064	cellular_component	ciliary basal body
M	0042981	biological_process	regulation of apoptotic process
M	0043531	molecular_function	ADP binding
M	0045296	molecular_function	cadherin binding
M	0045739	biological_process	positive regulation of DNA repair
M	0045893	biological_process	positive regulation of DNA-templated transcription
M	0045995	biological_process	regulation of embryonic development
M	0050821	biological_process	protein stabilization
M	0051117	molecular_function	ATPase binding
M	0051301	biological_process	cell division
M	0051726	biological_process	regulation of cell cycle
M	0060382	biological_process	regulation of DNA strand elongation
M	0070062	cellular_component	extracellular exosome
M	0071339	cellular_component	MLL1 complex
M	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
M	0090671	biological_process	telomerase RNA localization to Cajal body
M	0097255	cellular_component	R2TP complex
M	0101031	cellular_component	protein folding chaperone complex
M	0120293	cellular_component	dynein axonemal particle
M	1904507	biological_process	positive regulation of telomere maintenance in response to DNA damage
M	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
M	1990062	cellular_component	RPAP3/R2TP/prefoldin-like complex
M	1990904	cellular_component	ribonucleoprotein complex
M	2000779	biological_process	regulation of double-strand break repair
N	0000166	molecular_function	nucleotide binding
N	0000492	biological_process	box C/D snoRNP assembly
N	0000723	biological_process	telomere maintenance
N	0000786	cellular_component	nucleosome
N	0000791	cellular_component	euchromatin
N	0000812	cellular_component	Swr1 complex
N	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
N	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
N	0001094	molecular_function	TFIID-class transcription factor complex binding
N	0003678	molecular_function	DNA helicase activity
N	0003714	molecular_function	transcription corepressor activity
N	0004386	molecular_function	helicase activity
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006275	biological_process	regulation of DNA replication
N	0006281	biological_process	DNA repair
N	0006282	biological_process	regulation of DNA repair
N	0006310	biological_process	DNA recombination
N	0006325	biological_process	chromatin organization
N	0006338	biological_process	chromatin remodeling
N	0006355	biological_process	regulation of DNA-templated transcription
N	0006357	biological_process	regulation of transcription by RNA polymerase II
N	0006457	biological_process	protein folding
N	0006974	biological_process	DNA damage response
N	0008013	molecular_function	beta-catenin binding
N	0008094	molecular_function	ATP-dependent activity, acting on DNA
N	0016020	cellular_component	membrane
N	0016363	cellular_component	nuclear matrix
N	0016787	molecular_function	hydrolase activity
N	0016887	molecular_function	ATP hydrolysis activity
N	0017025	molecular_function	TBP-class protein binding
N	0031011	cellular_component	Ino80 complex
N	0031490	molecular_function	chromatin DNA binding
N	0033044	biological_process	regulation of chromosome organization
N	0034644	biological_process	cellular response to UV
N	0035267	cellular_component	NuA4 histone acetyltransferase complex
N	0042802	molecular_function	identical protein binding
N	0042803	molecular_function	protein homodimerization activity
N	0042981	biological_process	regulation of apoptotic process
N	0043531	molecular_function	ADP binding
N	0045739	biological_process	positive regulation of DNA repair
N	0045892	biological_process	negative regulation of DNA-templated transcription
N	0045893	biological_process	positive regulation of DNA-templated transcription
N	0045944	biological_process	positive regulation of transcription by RNA polymerase II
N	0045995	biological_process	regulation of embryonic development
N	0050821	biological_process	protein stabilization
N	0051082	molecular_function	unfolded protein binding
N	0051117	molecular_function	ATPase binding
N	0051726	biological_process	regulation of cell cycle
N	0060382	biological_process	regulation of DNA strand elongation
N	0070062	cellular_component	extracellular exosome
N	0071169	biological_process	establishment of protein localization to chromatin
N	0071339	cellular_component	MLL1 complex
N	0071392	biological_process	cellular response to estradiol stimulus
N	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
N	0090671	biological_process	telomerase RNA localization to Cajal body
N	0097255	cellular_component	R2TP complex
N	0101031	cellular_component	protein folding chaperone complex
N	0120293	cellular_component	dynein axonemal particle
N	0140585	molecular_function	promoter-enhancer loop anchoring activity
N	1904507	biological_process	positive regulation of telomere maintenance in response to DNA damage
N	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
N	1990062	cellular_component	RPAP3/R2TP/prefoldin-like complex
N	1990904	cellular_component	ribonucleoprotein complex
N	2000779	biological_process	regulation of double-strand break repair
O	0000166	molecular_function	nucleotide binding
O	0000492	biological_process	box C/D snoRNP assembly
O	0000723	biological_process	telomere maintenance
O	0000786	cellular_component	nucleosome
O	0000812	cellular_component	Swr1 complex
O	0001094	molecular_function	TFIID-class transcription factor complex binding
O	0003678	molecular_function	DNA helicase activity
O	0003713	molecular_function	transcription coactivator activity
O	0004386	molecular_function	helicase activity
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0005813	cellular_component	centrosome
O	0005829	cellular_component	cytosol
O	0006275	biological_process	regulation of DNA replication
O	0006281	biological_process	DNA repair
O	0006282	biological_process	regulation of DNA repair
O	0006310	biological_process	DNA recombination
O	0006325	biological_process	chromatin organization
O	0006338	biological_process	chromatin remodeling
O	0006355	biological_process	regulation of DNA-templated transcription
O	0006357	biological_process	regulation of transcription by RNA polymerase II
O	0006974	biological_process	DNA damage response
O	0007283	biological_process	spermatogenesis
O	0008094	molecular_function	ATP-dependent activity, acting on DNA
O	0016020	cellular_component	membrane
O	0016363	cellular_component	nuclear matrix
O	0016607	cellular_component	nuclear speck
O	0016787	molecular_function	hydrolase activity
O	0016887	molecular_function	ATP hydrolysis activity
O	0017025	molecular_function	TBP-class protein binding
O	0031011	cellular_component	Ino80 complex
O	0033044	biological_process	regulation of chromosome organization
O	0035267	cellular_component	NuA4 histone acetyltransferase complex
O	0036064	cellular_component	ciliary basal body
O	0042981	biological_process	regulation of apoptotic process
O	0043531	molecular_function	ADP binding
O	0045296	molecular_function	cadherin binding
O	0045739	biological_process	positive regulation of DNA repair
O	0045893	biological_process	positive regulation of DNA-templated transcription
O	0045995	biological_process	regulation of embryonic development
O	0050821	biological_process	protein stabilization
O	0051117	molecular_function	ATPase binding
O	0051301	biological_process	cell division
O	0051726	biological_process	regulation of cell cycle
O	0060382	biological_process	regulation of DNA strand elongation
O	0070062	cellular_component	extracellular exosome
O	0071339	cellular_component	MLL1 complex
O	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
O	0090671	biological_process	telomerase RNA localization to Cajal body
O	0097255	cellular_component	R2TP complex
O	0101031	cellular_component	protein folding chaperone complex
O	0120293	cellular_component	dynein axonemal particle
O	1904507	biological_process	positive regulation of telomere maintenance in response to DNA damage
O	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
O	1990062	cellular_component	RPAP3/R2TP/prefoldin-like complex
O	1990904	cellular_component	ribonucleoprotein complex
O	2000779	biological_process	regulation of double-strand break repair
P	0000166	molecular_function	nucleotide binding
P	0000492	biological_process	box C/D snoRNP assembly
P	0000723	biological_process	telomere maintenance
P	0000786	cellular_component	nucleosome
P	0000791	cellular_component	euchromatin
P	0000812	cellular_component	Swr1 complex
P	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
P	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
P	0001094	molecular_function	TFIID-class transcription factor complex binding
P	0003678	molecular_function	DNA helicase activity
P	0003714	molecular_function	transcription corepressor activity
P	0004386	molecular_function	helicase activity
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006275	biological_process	regulation of DNA replication
P	0006281	biological_process	DNA repair
P	0006282	biological_process	regulation of DNA repair
P	0006310	biological_process	DNA recombination
P	0006325	biological_process	chromatin organization
P	0006338	biological_process	chromatin remodeling
P	0006355	biological_process	regulation of DNA-templated transcription
P	0006357	biological_process	regulation of transcription by RNA polymerase II
P	0006457	biological_process	protein folding
P	0006974	biological_process	DNA damage response
P	0008013	molecular_function	beta-catenin binding
P	0008094	molecular_function	ATP-dependent activity, acting on DNA
P	0016020	cellular_component	membrane
P	0016363	cellular_component	nuclear matrix
P	0016787	molecular_function	hydrolase activity
P	0016887	molecular_function	ATP hydrolysis activity
P	0017025	molecular_function	TBP-class protein binding
P	0031011	cellular_component	Ino80 complex
P	0031490	molecular_function	chromatin DNA binding
P	0033044	biological_process	regulation of chromosome organization
P	0034644	biological_process	cellular response to UV
P	0035267	cellular_component	NuA4 histone acetyltransferase complex
P	0042802	molecular_function	identical protein binding
P	0042803	molecular_function	protein homodimerization activity
P	0042981	biological_process	regulation of apoptotic process
P	0043531	molecular_function	ADP binding
P	0045739	biological_process	positive regulation of DNA repair
P	0045892	biological_process	negative regulation of DNA-templated transcription
P	0045893	biological_process	positive regulation of DNA-templated transcription
P	0045944	biological_process	positive regulation of transcription by RNA polymerase II
P	0045995	biological_process	regulation of embryonic development
P	0050821	biological_process	protein stabilization
P	0051082	molecular_function	unfolded protein binding
P	0051117	molecular_function	ATPase binding
P	0051726	biological_process	regulation of cell cycle
P	0060382	biological_process	regulation of DNA strand elongation
P	0070062	cellular_component	extracellular exosome
P	0071169	biological_process	establishment of protein localization to chromatin
P	0071339	cellular_component	MLL1 complex
P	0071392	biological_process	cellular response to estradiol stimulus
P	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
P	0090671	biological_process	telomerase RNA localization to Cajal body
P	0097255	cellular_component	R2TP complex
P	0101031	cellular_component	protein folding chaperone complex
P	0120293	cellular_component	dynein axonemal particle
P	0140585	molecular_function	promoter-enhancer loop anchoring activity
P	1904507	biological_process	positive regulation of telomere maintenance in response to DNA damage
P	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
P	1990062	cellular_component	RPAP3/R2TP/prefoldin-like complex
P	1990904	cellular_component	ribonucleoprotein complex
P	2000779	biological_process	regulation of double-strand break repair
Q	0000166	molecular_function	nucleotide binding
Q	0000492	biological_process	box C/D snoRNP assembly
Q	0000723	biological_process	telomere maintenance
Q	0000786	cellular_component	nucleosome
Q	0000812	cellular_component	Swr1 complex
Q	0001094	molecular_function	TFIID-class transcription factor complex binding
Q	0003678	molecular_function	DNA helicase activity
Q	0003713	molecular_function	transcription coactivator activity
Q	0004386	molecular_function	helicase activity
Q	0005515	molecular_function	protein binding
Q	0005524	molecular_function	ATP binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005813	cellular_component	centrosome
Q	0005829	cellular_component	cytosol
Q	0006275	biological_process	regulation of DNA replication
Q	0006281	biological_process	DNA repair
Q	0006282	biological_process	regulation of DNA repair
Q	0006310	biological_process	DNA recombination
Q	0006325	biological_process	chromatin organization
Q	0006338	biological_process	chromatin remodeling
Q	0006355	biological_process	regulation of DNA-templated transcription
Q	0006357	biological_process	regulation of transcription by RNA polymerase II
Q	0006974	biological_process	DNA damage response
Q	0007283	biological_process	spermatogenesis
Q	0008094	molecular_function	ATP-dependent activity, acting on DNA
Q	0016020	cellular_component	membrane
Q	0016363	cellular_component	nuclear matrix
Q	0016607	cellular_component	nuclear speck
Q	0016787	molecular_function	hydrolase activity
Q	0016887	molecular_function	ATP hydrolysis activity
Q	0017025	molecular_function	TBP-class protein binding
Q	0031011	cellular_component	Ino80 complex
Q	0033044	biological_process	regulation of chromosome organization
Q	0035267	cellular_component	NuA4 histone acetyltransferase complex
Q	0036064	cellular_component	ciliary basal body
Q	0042981	biological_process	regulation of apoptotic process
Q	0043531	molecular_function	ADP binding
Q	0045296	molecular_function	cadherin binding
Q	0045739	biological_process	positive regulation of DNA repair
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0045995	biological_process	regulation of embryonic development
Q	0050821	biological_process	protein stabilization
Q	0051117	molecular_function	ATPase binding
Q	0051301	biological_process	cell division
Q	0051726	biological_process	regulation of cell cycle
Q	0060382	biological_process	regulation of DNA strand elongation
Q	0070062	cellular_component	extracellular exosome
Q	0071339	cellular_component	MLL1 complex
Q	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
Q	0090671	biological_process	telomerase RNA localization to Cajal body
Q	0097255	cellular_component	R2TP complex
Q	0101031	cellular_component	protein folding chaperone complex
Q	0120293	cellular_component	dynein axonemal particle
Q	1904507	biological_process	positive regulation of telomere maintenance in response to DNA damage
Q	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
Q	1990062	cellular_component	RPAP3/R2TP/prefoldin-like complex
Q	1990904	cellular_component	ribonucleoprotein complex
Q	2000779	biological_process	regulation of double-strand break repair
R	0000166	molecular_function	nucleotide binding
R	0000492	biological_process	box C/D snoRNP assembly
R	0000723	biological_process	telomere maintenance
R	0000786	cellular_component	nucleosome
R	0000791	cellular_component	euchromatin
R	0000812	cellular_component	Swr1 complex
R	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
R	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
R	0001094	molecular_function	TFIID-class transcription factor complex binding
R	0003678	molecular_function	DNA helicase activity
R	0003714	molecular_function	transcription corepressor activity
R	0004386	molecular_function	helicase activity
R	0005515	molecular_function	protein binding
R	0005524	molecular_function	ATP binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006275	biological_process	regulation of DNA replication
R	0006281	biological_process	DNA repair
R	0006282	biological_process	regulation of DNA repair
R	0006310	biological_process	DNA recombination
R	0006325	biological_process	chromatin organization
R	0006338	biological_process	chromatin remodeling
R	0006355	biological_process	regulation of DNA-templated transcription
R	0006357	biological_process	regulation of transcription by RNA polymerase II
R	0006457	biological_process	protein folding
R	0006974	biological_process	DNA damage response
R	0008013	molecular_function	beta-catenin binding
R	0008094	molecular_function	ATP-dependent activity, acting on DNA
R	0016020	cellular_component	membrane
R	0016363	cellular_component	nuclear matrix
R	0016787	molecular_function	hydrolase activity
R	0016887	molecular_function	ATP hydrolysis activity
R	0017025	molecular_function	TBP-class protein binding
R	0031011	cellular_component	Ino80 complex
R	0031490	molecular_function	chromatin DNA binding
R	0033044	biological_process	regulation of chromosome organization
R	0034644	biological_process	cellular response to UV
R	0035267	cellular_component	NuA4 histone acetyltransferase complex
R	0042802	molecular_function	identical protein binding
R	0042803	molecular_function	protein homodimerization activity
R	0042981	biological_process	regulation of apoptotic process
R	0043531	molecular_function	ADP binding
R	0045739	biological_process	positive regulation of DNA repair
R	0045892	biological_process	negative regulation of DNA-templated transcription
R	0045893	biological_process	positive regulation of DNA-templated transcription
R	0045944	biological_process	positive regulation of transcription by RNA polymerase II
R	0045995	biological_process	regulation of embryonic development
R	0050821	biological_process	protein stabilization
R	0051082	molecular_function	unfolded protein binding
R	0051117	molecular_function	ATPase binding
R	0051726	biological_process	regulation of cell cycle
R	0060382	biological_process	regulation of DNA strand elongation
R	0070062	cellular_component	extracellular exosome
R	0071169	biological_process	establishment of protein localization to chromatin
R	0071339	cellular_component	MLL1 complex
R	0071392	biological_process	cellular response to estradiol stimulus
R	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
R	0090671	biological_process	telomerase RNA localization to Cajal body
R	0097255	cellular_component	R2TP complex
R	0101031	cellular_component	protein folding chaperone complex
R	0120293	cellular_component	dynein axonemal particle
R	0140585	molecular_function	promoter-enhancer loop anchoring activity
R	1904507	biological_process	positive regulation of telomere maintenance in response to DNA damage
R	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
R	1990062	cellular_component	RPAP3/R2TP/prefoldin-like complex
R	1990904	cellular_component	ribonucleoprotein complex
R	2000779	biological_process	regulation of double-strand break repair
S	0000166	molecular_function	nucleotide binding
S	0000776	cellular_component	kinetochore
S	0000785	cellular_component	chromatin
S	0000786	cellular_component	nucleosome
S	0000930	cellular_component	gamma-tubulin complex
S	0001738	biological_process	morphogenesis of a polarized epithelium
S	0005200	molecular_function	structural constituent of cytoskeleton
S	0005515	molecular_function	protein binding
S	0005524	molecular_function	ATP binding
S	0005615	cellular_component	extracellular space
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005856	cellular_component	cytoskeleton
S	0005869	cellular_component	dynactin complex
S	0005884	cellular_component	actin filament
S	0005886	cellular_component	plasma membrane
S	0005903	cellular_component	brush border
S	0005911	cellular_component	cell-cell junction
S	0005912	cellular_component	adherens junction
S	0005925	cellular_component	focal adhesion
S	0006338	biological_process	chromatin remodeling
S	0006357	biological_process	regulation of transcription by RNA polymerase II
S	0007010	biological_process	cytoskeleton organization
S	0007017	biological_process	microtubule-based process
S	0007020	biological_process	microtubule nucleation
S	0007163	biological_process	establishment or maintenance of cell polarity
S	0007409	biological_process	axonogenesis
S	0008284	biological_process	positive regulation of cell population proliferation
S	0015629	cellular_component	actin cytoskeleton
S	0016020	cellular_component	membrane
S	0016363	cellular_component	nuclear matrix
S	0016514	cellular_component	SWI/SNF complex
S	0016586	cellular_component	RSC-type complex
S	0016787	molecular_function	hydrolase activity
S	0016887	molecular_function	ATP hydrolysis activity
S	0019894	molecular_function	kinesin binding
S	0019901	molecular_function	protein kinase binding
S	0021762	biological_process	substantia nigra development
S	0030027	cellular_component	lamellipodium
S	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
S	0030235	molecular_function	nitric-oxide synthase regulator activity
S	0030424	cellular_component	axon
S	0030863	cellular_component	cortical cytoskeleton
S	0030957	molecular_function	Tat protein binding
S	0031492	molecular_function	nucleosomal DNA binding
S	0031982	cellular_component	vesicle
S	0032991	cellular_component	protein-containing complex
S	0034333	biological_process	adherens junction assembly
S	0035060	cellular_component	brahma complex
S	0035267	cellular_component	NuA4 histone acetyltransferase complex
S	0035633	biological_process	maintenance of blood-brain barrier
S	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
S	0042802	molecular_function	identical protein binding
S	0042981	biological_process	regulation of apoptotic process
S	0043296	cellular_component	apical junction complex
S	0044305	cellular_component	calyx of Held
S	0045176	biological_process	apical protein localization
S	0045202	cellular_component	synapse
S	0045582	biological_process	positive regulation of T cell differentiation
S	0045596	biological_process	negative regulation of cell differentiation
S	0045597	biological_process	positive regulation of cell differentiation
S	0045663	biological_process	positive regulation of myoblast differentiation
S	0045893	biological_process	positive regulation of DNA-templated transcription
S	0048156	molecular_function	tau protein binding
S	0048870	biological_process	cell motility
S	0050998	molecular_function	nitric-oxide synthase binding
S	0051621	biological_process	regulation of norepinephrine uptake
S	0051623	biological_process	positive regulation of norepinephrine uptake
S	0051726	biological_process	regulation of cell cycle
S	0070062	cellular_component	extracellular exosome
S	0070160	cellular_component	tight junction
S	0070316	biological_process	regulation of G0 to G1 transition
S	0070527	biological_process	platelet aggregation
S	0071564	cellular_component	npBAF complex
S	0071565	cellular_component	nBAF complex
S	0071896	biological_process	protein localization to adherens junction
S	0072562	cellular_component	blood microparticle
S	0072749	biological_process	cellular response to cytochalasin B
S	0097433	cellular_component	dense body
S	0098685	cellular_component	Schaffer collateral - CA1 synapse
S	0098793	cellular_component	presynapse
S	0098871	cellular_component	postsynaptic actin cytoskeleton
S	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
S	0098974	biological_process	postsynaptic actin cytoskeleton organization
S	0098978	cellular_component	glutamatergic synapse
S	0140092	cellular_component	bBAF complex
S	0140288	cellular_component	GBAF complex
S	0141108	molecular_function	transporter regulator activity
S	0150111	biological_process	regulation of transepithelial transport
S	1900242	biological_process	regulation of synaptic vesicle endocytosis
S	1902459	biological_process	positive regulation of stem cell population maintenance
S	1903076	biological_process	regulation of protein localization to plasma membrane
S	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
S	1990904	cellular_component	ribonucleoprotein complex
S	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
S	2000779	biological_process	regulation of double-strand break repair
S	2000781	biological_process	positive regulation of double-strand break repair
S	2000819	biological_process	regulation of nucleotide-excision repair
T	0000723	biological_process	telomere maintenance
T	0000776	cellular_component	kinetochore
T	0000785	cellular_component	chromatin
T	0000786	cellular_component	nucleosome
T	0003407	biological_process	neural retina development
T	0003682	molecular_function	chromatin binding
T	0003713	molecular_function	transcription coactivator activity
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005886	cellular_component	plasma membrane
T	0006275	biological_process	regulation of DNA replication
T	0006281	biological_process	DNA repair
T	0006282	biological_process	regulation of DNA repair
T	0006310	biological_process	DNA recombination
T	0006325	biological_process	chromatin organization
T	0006338	biological_process	chromatin remodeling
T	0006355	biological_process	regulation of DNA-templated transcription
T	0006357	biological_process	regulation of transcription by RNA polymerase II
T	0006974	biological_process	DNA damage response
T	0007165	biological_process	signal transduction
T	0007399	biological_process	nervous system development
T	0008284	biological_process	positive regulation of cell population proliferation
T	0016363	cellular_component	nuclear matrix
T	0016514	cellular_component	SWI/SNF complex
T	0016586	cellular_component	RSC-type complex
T	0021510	biological_process	spinal cord development
T	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
T	0031011	cellular_component	Ino80 complex
T	0031492	molecular_function	nucleosomal DNA binding
T	0032991	cellular_component	protein-containing complex
T	0033044	biological_process	regulation of chromosome organization
T	0035060	cellular_component	brahma complex
T	0035267	cellular_component	NuA4 histone acetyltransferase complex
T	0042981	biological_process	regulation of apoptotic process
T	0045582	biological_process	positive regulation of T cell differentiation
T	0045596	biological_process	negative regulation of cell differentiation
T	0045597	biological_process	positive regulation of cell differentiation
T	0045663	biological_process	positive regulation of myoblast differentiation
T	0045739	biological_process	positive regulation of DNA repair
T	0045893	biological_process	positive regulation of DNA-templated transcription
T	0045995	biological_process	regulation of embryonic development
T	0048731	biological_process	system development
T	0051726	biological_process	regulation of cell cycle
T	0060382	biological_process	regulation of DNA strand elongation
T	0070316	biological_process	regulation of G0 to G1 transition
T	0071564	cellular_component	npBAF complex
T	0140288	cellular_component	GBAF complex
T	1902459	biological_process	positive regulation of stem cell population maintenance
T	1904507	biological_process	positive regulation of telomere maintenance in response to DNA damage
T	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
T	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
T	2000779	biological_process	regulation of double-strand break repair
T	2000781	biological_process	positive regulation of double-strand break repair
T	2000819	biological_process	regulation of nucleotide-excision repair
U	0000166	molecular_function	nucleotide binding
U	0000776	cellular_component	kinetochore
U	0000785	cellular_component	chromatin
U	0000786	cellular_component	nucleosome
U	0000930	cellular_component	gamma-tubulin complex
U	0001738	biological_process	morphogenesis of a polarized epithelium
U	0005200	molecular_function	structural constituent of cytoskeleton
U	0005515	molecular_function	protein binding
U	0005524	molecular_function	ATP binding
U	0005615	cellular_component	extracellular space
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005856	cellular_component	cytoskeleton
U	0005869	cellular_component	dynactin complex
U	0005884	cellular_component	actin filament
U	0005886	cellular_component	plasma membrane
U	0005903	cellular_component	brush border
U	0005911	cellular_component	cell-cell junction
U	0005912	cellular_component	adherens junction
U	0005925	cellular_component	focal adhesion
U	0006338	biological_process	chromatin remodeling
U	0006357	biological_process	regulation of transcription by RNA polymerase II
U	0007010	biological_process	cytoskeleton organization
U	0007017	biological_process	microtubule-based process
U	0007020	biological_process	microtubule nucleation
U	0007163	biological_process	establishment or maintenance of cell polarity
U	0007409	biological_process	axonogenesis
U	0008284	biological_process	positive regulation of cell population proliferation
U	0015629	cellular_component	actin cytoskeleton
U	0016020	cellular_component	membrane
U	0016363	cellular_component	nuclear matrix
U	0016514	cellular_component	SWI/SNF complex
U	0016586	cellular_component	RSC-type complex
U	0016787	molecular_function	hydrolase activity
U	0016887	molecular_function	ATP hydrolysis activity
U	0019894	molecular_function	kinesin binding
U	0019901	molecular_function	protein kinase binding
U	0021762	biological_process	substantia nigra development
U	0030027	cellular_component	lamellipodium
U	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
U	0030235	molecular_function	nitric-oxide synthase regulator activity
U	0030424	cellular_component	axon
U	0030863	cellular_component	cortical cytoskeleton
U	0030957	molecular_function	Tat protein binding
U	0031492	molecular_function	nucleosomal DNA binding
U	0031982	cellular_component	vesicle
U	0032991	cellular_component	protein-containing complex
U	0034333	biological_process	adherens junction assembly
U	0035060	cellular_component	brahma complex
U	0035267	cellular_component	NuA4 histone acetyltransferase complex
U	0035633	biological_process	maintenance of blood-brain barrier
U	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
U	0042802	molecular_function	identical protein binding
U	0042981	biological_process	regulation of apoptotic process
U	0043296	cellular_component	apical junction complex
U	0044305	cellular_component	calyx of Held
U	0045176	biological_process	apical protein localization
U	0045202	cellular_component	synapse
U	0045582	biological_process	positive regulation of T cell differentiation
U	0045596	biological_process	negative regulation of cell differentiation
U	0045597	biological_process	positive regulation of cell differentiation
U	0045663	biological_process	positive regulation of myoblast differentiation
U	0045893	biological_process	positive regulation of DNA-templated transcription
U	0048156	molecular_function	tau protein binding
U	0048870	biological_process	cell motility
U	0050998	molecular_function	nitric-oxide synthase binding
U	0051621	biological_process	regulation of norepinephrine uptake
U	0051623	biological_process	positive regulation of norepinephrine uptake
U	0051726	biological_process	regulation of cell cycle
U	0070062	cellular_component	extracellular exosome
U	0070160	cellular_component	tight junction
U	0070316	biological_process	regulation of G0 to G1 transition
U	0070527	biological_process	platelet aggregation
U	0071564	cellular_component	npBAF complex
U	0071565	cellular_component	nBAF complex
U	0071896	biological_process	protein localization to adherens junction
U	0072562	cellular_component	blood microparticle
U	0072749	biological_process	cellular response to cytochalasin B
U	0097433	cellular_component	dense body
U	0098685	cellular_component	Schaffer collateral - CA1 synapse
U	0098793	cellular_component	presynapse
U	0098871	cellular_component	postsynaptic actin cytoskeleton
U	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
U	0098974	biological_process	postsynaptic actin cytoskeleton organization
U	0098978	cellular_component	glutamatergic synapse
U	0140092	cellular_component	bBAF complex
U	0140288	cellular_component	GBAF complex
U	0141108	molecular_function	transporter regulator activity
U	0150111	biological_process	regulation of transepithelial transport
U	1900242	biological_process	regulation of synaptic vesicle endocytosis
U	1902459	biological_process	positive regulation of stem cell population maintenance
U	1903076	biological_process	regulation of protein localization to plasma membrane
U	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
U	1990904	cellular_component	ribonucleoprotein complex
U	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
U	2000779	biological_process	regulation of double-strand break repair
U	2000781	biological_process	positive regulation of double-strand break repair
U	2000819	biological_process	regulation of nucleotide-excision repair
V	0000122	biological_process	negative regulation of transcription by RNA polymerase II
V	0000786	cellular_component	nucleosome
V	0000812	cellular_component	Swr1 complex
V	0003714	molecular_function	transcription corepressor activity
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005657	cellular_component	replication fork
V	0005694	cellular_component	chromosome
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006281	biological_process	DNA repair
V	0006325	biological_process	chromatin organization
V	0006338	biological_process	chromatin remodeling
V	0006355	biological_process	regulation of DNA-templated transcription
V	0035267	cellular_component	NuA4 histone acetyltransferase complex
V	0042307	biological_process	positive regulation of protein import into nucleus
V	0042981	biological_process	regulation of apoptotic process
V	0045471	biological_process	response to ethanol
V	0045892	biological_process	negative regulation of DNA-templated transcription
V	0045893	biological_process	positive regulation of DNA-templated transcription
V	0051726	biological_process	regulation of cell cycle
V	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
V	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
V	2000779	biological_process	regulation of double-strand break repair
W	0000278	biological_process	mitotic cell cycle
W	0000786	cellular_component	nucleosome
W	0005200	molecular_function	structural constituent of cytoskeleton
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0006325	biological_process	chromatin organization
W	0006338	biological_process	chromatin remodeling
W	0006355	biological_process	regulation of DNA-templated transcription
W	0006357	biological_process	regulation of transcription by RNA polymerase II
W	0007010	biological_process	cytoskeleton organization
W	0016363	cellular_component	nuclear matrix
W	0035267	cellular_component	NuA4 histone acetyltransferase complex
W	0042393	molecular_function	histone binding
W	0042981	biological_process	regulation of apoptotic process
W	0045893	biological_process	positive regulation of DNA-templated transcription
W	0051726	biological_process	regulation of cell cycle
W	0140044	molecular_function	histone H3K18ac reader activity
W	0140119	molecular_function	histone H3K27ac reader activity
W	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
W	2000779	biological_process	regulation of double-strand break repair

Functional Information from PROSITE/UniProt

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
A	ALA21-VAL27

---

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
D	GLY14-HIS18

---

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LILDSGATHTTA

Chain	Residue	Details
T	LEU168-ALA179

---

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
C	LYS14-LEU20

---

site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
B	ARG89-GLY111

---

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
S	TYR53-GLY63

---

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
S	TRP356-GLU364
T	TRP410-GLU418

---

site_id	PS00959
Number of Residues	9
Details	HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI

Chain	Residue	Details
C	PRO66-ILE74

---

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
S	LEU104-ARG116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N6-(beta-hydroxybutyryl)lysine; alternate","evidences":[{"source":"PubMed","id":"27105115","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6-crotonyllysine; alternate","evidences":[{"source":"PubMed","id":"21925322","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N6-(2-hydroxyisobutyryl)lysine","evidences":[{"source":"PubMed","id":"24681537","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"22389435","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"N5-methylglutamine","evidences":[{"source":"PubMed","id":"24352239","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Modified residue: {"description":"N6-glutaryllysine; alternate","evidences":[{"source":"PubMed","id":"31542297","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by DCAF1","evidences":[{"source":"PubMed","id":"15078818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24140421","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"22713238","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22980979","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"15386022","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16359901","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16702407","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25470042","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22713238","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22980979","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	Modified residue: {"description":"PolyADP-ribosyl glutamic acid","evidences":[{"source":"UniProtKB","id":"Q64475","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by AMPK","evidences":[{"source":"UniProtKB","id":"Q6ZWY9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Modified residue: {"description":"N6-lactoyllysine; alternate","evidences":[{"source":"PubMed","id":"31645732","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	4
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"16627869","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	Modified residue: {"description":"N6-(2-hydroxyisobutyryl)lysine; alternate","evidences":[{"source":"PubMed","id":"24681537","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Modified residue: {"description":"Dimethylated arginine","evidences":[{"source":"UniProtKB","id":"Q96A08","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	4
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"Q96A08","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q00729","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"source":"PubMed","id":"22121020","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"21726816","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"16307923","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16627869","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16713563","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22121020","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19783980","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20850016","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"16267050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17194708","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"22389435","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29211711","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20850016","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P84243","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"22389435","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27436229","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	2
Details	Modified residue: {"description":"N6-propionyllysine; alternate","evidences":[{"source":"PubMed","id":"17267393","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by PAK2","evidences":[{"source":"PubMed","id":"21724829","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62806","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P62806","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate","evidences":[{"source":"PubMed","id":"30886146","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"19818714","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	7
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	72
Details	Domain: {"description":"HSA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00549","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	165
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	153
Details	Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	32
Details	Zinc finger: {"description":"HIT-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00453","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	66
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	9
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"PubMed","id":"17892483","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00453","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by MAPK11 and MAPK14","evidences":[{"source":"PubMed","id":"17380123","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	21
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	16
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	21
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"36173861","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	2
Details	Modified residue: {"description":"N-acetylaspartate; in Actin, cytoplasmic 1, N-terminally processed","evidences":[{"source":"PubMed","id":"29581253","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30028079","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2005","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	2
Details	Modified residue: {"description":"Methionine (R)-sulfoxide","evidences":[{"source":"PubMed","id":"29343822","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	2
Details	Modified residue: {"description":"Tele-methylhistidine","evidences":[{"source":"PubMed","id":"30526847","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30626964","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30785395","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31388018","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32503840","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	2
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"23673617","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	1
Details	Cross-link: {"description":"(Microbial infection) Isoglutamyl lysine isopeptide (Lys-Glu) (interchain with E-270); by Vibrio toxins RtxA and VgrG1","evidences":[{"source":"PubMed","id":"19015515","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	4
Details	Cross-link: {"description":"(Microbial infection) Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-50); by Vibrio toxins RtxA and VgrG1","evidences":[{"source":"PubMed","id":"19015515","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	50
Details	Domain: {"description":"SANT"}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	9
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	4
Details	Region: {"description":"Diacetylated histone H3 binding","evidences":[{"source":"PubMed","id":"29900004","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30071723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VNB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XTZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	1
Details	Site: {"description":"Interacts with diacetylated histone H3","evidences":[{"source":"PubMed","id":"29900004","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30071723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VNB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XTZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---