8WYS
Local map of human CD5L bound to IgM-Fc/J
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| M | 0002376 | biological_process | immune system process |
| M | 0005576 | cellular_component | extracellular region |
| M | 0005615 | cellular_component | extracellular space |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0005886 | cellular_component | plasma membrane |
| M | 0006915 | biological_process | apoptotic process |
| M | 0006954 | biological_process | inflammatory response |
| M | 0006968 | biological_process | cellular defense response |
| M | 0009986 | cellular_component | cell surface |
| M | 0016020 | cellular_component | membrane |
| M | 0030449 | biological_process | regulation of complement activation |
| M | 0072562 | cellular_component | blood microparticle |
| M | 1903661 | biological_process | positive regulation of complement-dependent cytotoxicity |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FTCRVDH |
| Chain | Residue | Details |
| A | PHE318-HIS324 | |
| A | PHE424-HIS430 | |
| A | TYR534-HIS540 |
| site_id | PS00420 |
| Number of Residues | 38 |
| Details | SRCR_1 SRCR domain signature. GlhrceGrvEveqkgqWGtvCddgWdikdvavlCrelG |
| Chain | Residue | Details |
| M | GLY29-GLY66 | |
| M | GLY249-GLY286 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:25946035, ECO:0000269|PubMed:407930 |
| Chain | Residue | Details |
| J | GLN0 | |
| L | ASN332 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| J | ASN48 | |
| L | ASN395 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:35981043, ECO:0000269|PubMed:4742735, ECO:0007744|PDB:7XQ8 |
| Chain | Residue | Details |
| A | ASN402 | |
| L | ASN402 |
