8WQQ
Proteomics study reveals that ASFV g5Rp protein interacts with eukaryotic translation initiation factor 5A and may regulate host translation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004081 | molecular_function | bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity |
| A | 0006167 | biological_process | AMP biosynthetic process |
| A | 0006754 | biological_process | ATP biosynthetic process |
| A | 0008486 | molecular_function | diphosphoinositol-polyphosphate diphosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0039657 | biological_process | symbiont-mediated suppression of host gene expression |
| A | 0044168 | cellular_component | host cell rough endoplasmic reticulum |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004081 | molecular_function | bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity |
| B | 0006167 | biological_process | AMP biosynthetic process |
| B | 0006754 | biological_process | ATP biosynthetic process |
| B | 0008486 | molecular_function | diphosphoinositol-polyphosphate diphosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0039657 | biological_process | symbiont-mediated suppression of host gene expression |
| B | 0044168 | cellular_component | host cell rough endoplasmic reticulum |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS00893 |
| Number of Residues | 22 |
| Details | NUDIX_BOX Nudix box signature. GkpkedEsdltCAiREFeEEtG |
| Chain | Residue | Details |
| A | GLY128-GLY149 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 284 |
| Details | Domain: {"description":"Nudix hydrolase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Motif: {"description":"Nudix box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"19695654","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
