8WME
Crystal Structure of Drosophila melanogaster D46A Dopamine N-Acetyltransferase
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22716280, ECO:0007744|PDB:3TE4 |
| Chain | Residue | Details |
| B | LEU146 | |
| B | GLY154 | |
| A | LEU146 | |
| A | GLY154 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Has a role in the catalytic activity => ECO:0000269|PubMed:25406072 |
| Chain | Residue | Details |
| B | GLU47 | |
| B | SER182 | |
| B | SER186 | |
| A | GLU47 | |
| A | SER182 | |
| A | SER186 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Might be involved in substrate binding => ECO:0000269|PubMed:25406072 |
| Chain | Residue | Details |
| B | TYR64 | |
| A | TYR64 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Regulates binding affinity for coenzyme A (CoASH) => ECO:0000269|PubMed:25406072 |
| Chain | Residue | Details |
| B | ARG153 | |
| A | ARG153 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Acetyl-CoA => ECO:0000269|PubMed:22716280, ECO:0007744|PDB:3TE4 |
| Chain | Residue | Details |
| B | LYS192 | |
| A | LYS192 |
