8WME

Crystal Structure of Drosophila melanogaster D46A Dopamine N-Acetyltransferase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	146
Details	Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22716280","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3TE4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Site: {"description":"Has a role in the catalytic activity","evidences":[{"source":"PubMed","id":"25406072","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Might be involved in substrate binding","evidences":[{"source":"PubMed","id":"25406072","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Site: {"description":"Regulates binding affinity for coenzyme A (CoASH)","evidences":[{"source":"PubMed","id":"25406072","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Site: {"description":"Acetyl-CoA","evidences":[{"source":"PubMed","id":"22716280","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3TE4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---