8WM5
multidrug transporter EfpA from Mycobacterium tuberculosis bound with lipids
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 270 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-SER50 | |
| B | ASP113-ARG119 | |
| B | LYS172-THR180 | |
| B | ARG225-ASP239 | |
| B | GLU288-ARG306 | |
| B | SER365-ARG370 | |
| B | SER422-ALA437 | |
| B | TYR510-LEU530 | |
| A | ASP113-ARG119 | |
| A | LYS172-THR180 | |
| A | ARG225-ASP239 | |
| A | GLU288-ARG306 | |
| A | SER365-ARG370 | |
| A | SER422-ALA437 | |
| A | TYR510-LEU530 | |
| B | MET1-SER50 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 560 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE51-VAL71 | |
| A | VAL344-VAL364 | |
| A | VAL371-MET391 | |
| A | LEU401-LEU421 | |
| A | ILE438-ILE458 | |
| A | TYR489-GLY509 | |
| B | PHE51-VAL71 | |
| B | TRP92-GLY112 | |
| B | THR120-ASP140 | |
| B | GLN151-PRO171 | |
| B | ALA181-LEU201 | |
| A | TRP92-GLY112 | |
| B | VAL204-ALA224 | |
| B | ALA240-GLY260 | |
| B | SER267-VAL287 | |
| B | LEU307-ILE327 | |
| B | VAL344-VAL364 | |
| B | VAL371-MET391 | |
| B | LEU401-LEU421 | |
| B | ILE438-ILE458 | |
| B | TYR489-GLY509 | |
| A | THR120-ASP140 | |
| A | GLN151-PRO171 | |
| A | ALA181-LEU201 | |
| A | VAL204-ALA224 | |
| A | ALA240-GLY260 | |
| A | SER267-VAL287 | |
| A | LEU307-ILE327 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 172 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA72-SER91 | |
| B | THR202-GLU203 | |
| B | PRO261-MET266 | |
| B | GLY328-GLY343 | |
| B | HIS392-ASN400 | |
| B | THR459-THR488 | |
| A | GLU141-SER150 | |
| A | THR202-GLU203 | |
| A | PRO261-MET266 | |
| A | GLY328-GLY343 | |
| A | HIS392-ASN400 | |
| A | THR459-THR488 | |
| B | ALA72-SER91 | |
| B | GLU141-SER150 |
